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- 详细信息
- 用户评价
- 文献和实验
- 技术资料
- 抗体名:
STAT3(Phospho-Ser727)
- 抗体英文名:
STAT3(Phospho-Ser727) Antibody
- 靶点:
STAT3
- 浓度:
1.0mg/ml
- 应用范围:
WB IHC IF
- 宿主:
Rabbit
- 适应物种:
Hu Ms Rt
- 克隆性:
多克隆
- 保存条件:
Store at -20℃
- 形态:
liquid
- 免疫原:
Peptide sequence around phosphorylation site of serine 727 (P-M-S(p)-P-R) derived from Human STAT3.
STAT3(Phospho-Ser727) Antibody
Host Species:
Rabbit
Clonality:
Polyclonal
Purification:
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Applications:
WB IHC IF
Species Reactivity:
Hu Ms Rt
Specificity:
The antibody detects endogenous level of STAT3 only when phosphorylated at serine 727.
Immunogen Type:
Peptide-KLH
Immunogen Description:
Peptide sequence around phosphorylation site of serine 727 (P-M-S(p)-P-R) derived from Human STAT3.
Target Name:
STAT3
Modification:
Phospho
Alternative Names:
APRF, HIES
Uniprot:
P40763
Gene ID:
6774;
Accession No.:
Swiss-Prot: P40763
NCBI Protein: NP_003141.2
Western blot analysis of extracts from Hela and HepG2 cells untreated or treated with P-M-A usingSTAT3(Phospho-Ser727) Antibody #11046.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3(Phospho-Ser727) Antibody #11046(left) or the same antibody preincubated with blocking peptide(right).
Immunofluorescence staining of methanol-fixed Hela cells using STAT3(Phospho-Ser727) Antibody #11046.
Western blot analysis of extracts from Hela cells, treated with IFNa or calf intestinal phosphatase (CIP), using STAT3 (Phospho-Ser727) Antibody #11046.
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文献和实验PMID: 31994797
A thiazole-derived oridonIn analogue exhibits antitumor activity by directly and allosterically InhibitIng STAT3. In J Biol Chem on 2019 Nov 15;by Shen X, Zhao L,et al..PMID:31594861, , (2019),
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PMID: 27465400
Prognostic significance of serine-phosphorylated STAT3 expression in pT1-T2 oral tongue carcinoma.In Clin Exp Otorhinolaryngol On 2015 Sep by Elena Fasanaro , Claudia Staffieri et al..PMID:26330924, , (2015),
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