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STAT3(Phospho-Ser727) Antibody

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  • 询价
  • Signalway Antibody已认证
  • 11046
  • USA
  • 2025年07月15日
  • WB IHC IF
  • Rabbit
  • Hu Ms Rt
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    • 详细信息
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    • 技术资料
    • 抗体名

      STAT3(Phospho-Ser727)

    • 抗体英文名

      STAT3(Phospho-Ser727) Antibody

    • 靶点

      STAT3

    • 浓度

      1.0mg/ml

    • 应用范围

      WB IHC IF

    • 宿主

      Rabbit

    • 适应物种

      Hu Ms Rt

    • 克隆性

      多克隆

    • 保存条件

      Store at -20℃

    • 形态

      liquid

    • 免疫原

      Peptide sequence around phosphorylation site of serine 727 (P-M-S(p)-P-R) derived from Human STAT3.

    Product Name
    STAT3(Phospho-Ser727) Antibody

    Host Species:
    Rabbit

    Clonality:
    Polyclonal

    Purification:
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

    Applications:
    WB IHC IF

    Species Reactivity:
    Hu Ms Rt

    Specificity:
    The antibody detects endogenous level of STAT3 only when phosphorylated at serine 727.

    Immunogen Type:
    Peptide-KLH

    Immunogen Description:
    Peptide sequence around phosphorylation site of serine 727 (P-M-S(p)-P-R) derived from Human STAT3.

    Target Name:
    STAT3

    Modification:
    Phospho

    Alternative Names:
    APRF, HIES

    Uniprot:
    P40763

    Gene ID:
    6774;

    Accession No.:
    Swiss-Prot: P40763
    NCBI Protein: NP_003141.2

    产品细节图片1

    Western blot analysis of extracts from Hela and HepG2 cells untreated or treated with P-M-A usingSTAT3(Phospho-Ser727) Antibody #11046.

    产品细节图片2
    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3(Phospho-Ser727) Antibody #11046(left) or the same antibody preincubated with blocking peptide(right).
    产品细节图片3
    Immunofluorescence staining of methanol-fixed Hela cells using STAT3(Phospho-Ser727) Antibody #11046.

    产品细节图片4
    Western blot analysis of extracts from Hela cells, treated with IFNa or calf intestinal phosphatase (CIP), using STAT3 (Phospho-Ser727) Antibody #11046.

     

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      图标文献和实验
      该产品被引用文献
      Anti inflammatory and metabolic reprogramming effects of MENK produce antitumor response in CT26 tumor bearing mice.In J Leukoc Biol on 2020 Jan 29. by Tuo Y, Zhang Z, et al..PMID:31994797, , (2020),
      PMID: 31994797

      A thiazole-derived oridonIn analogue exhibits antitumor activity by directly and allosterically InhibitIng STAT3. In J Biol Chem on 2019 Nov 15;by Shen X, Zhao L,et al..PMID:31594861, , (2019),
      PMID: 31594861

      Migration Suppression of Small Cell Lung Cancer by Polysaccharides from Nostoc commune Vaucher. In J Agric Food Chem on 2016 Aug 17 by Min Guo, Guo-Bin Ding,et al..PMID: 27465400, , (2016),
      PMID: 27465400

      Prognostic significance of serine-phosphorylated STAT3 expression in pT1-T2 oral tongue carcinoma.In Clin Exp Otorhinolaryngol On 2015 Sep by Elena Fasanaro , Claudia Staffieri et al..PMID:26330924, , (2015),
      PMID: 26330924
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      资料下载:

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