Peptide sequence around phosphorylation site of serine 727 (P-M-S(p)-P-R) derived from Human STAT3.
Product Name STAT3(Phospho-Ser727) Antibody
Host Species: Rabbit
Clonality: Polyclonal
Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Applications: WB IHC IF
Species Reactivity: Hu Ms Rt
Specificity: The antibody detects endogenous level of STAT3 only when phosphorylated at serine 727.
Immunogen Type: Peptide-KLH
Immunogen Description: Peptide sequence around phosphorylation site of serine 727 (P-M-S(p)-P-R) derived from Human STAT3.
Western blot analysis of extracts from Hela and HepG2 cells untreated or treated with P-M-A usingSTAT3(Phospho-Ser727) Antibody #11046.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3(Phospho-Ser727) Antibody #11046(left) or the same antibody preincubated with blocking peptide(right).
Immunofluorescence staining of methanol-fixed Hela cells using STAT3(Phospho-Ser727) Antibody #11046.
Western blot analysis of extracts from Hela cells, treated with IFNa or calf intestinal phosphatase (CIP), using STAT3 (Phospho-Ser727) Antibody #11046.
Anti inflammatory and metabolic reprogramming effects of MENK produce antitumor response in CT26 tumor bearing mice.In J Leukoc Biol on 2020 Jan 29. by Tuo Y, Zhang Z, et al..PMID:31994797, , (2020), PMID: 31994797
A thiazole-derived oridonIn analogue exhibits antitumor activity by directly and allosterically InhibitIng STAT3. In J Biol Chem on 2019 Nov 15;by Shen X, Zhao L,et al..PMID:31594861, , (2019), PMID: 31594861
Migration Suppression of Small Cell Lung Cancer by Polysaccharides from Nostoc commune Vaucher. In J Agric Food Chem on 2016 Aug 17 by Min Guo, Guo-Bin Ding,et al..PMID: 27465400, , (2016), PMID: 27465400
Prognostic significance of serine-phosphorylated STAT3 expression in pT1-T2 oral tongue carcinoma.In Clin Exp Otorhinolaryngol On 2015 Sep by Elena Fasanaro , Claudia Staffieri et al..PMID:26330924, , (2015), PMID: 26330924