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- 详细信息
- 用户评价
- 文献和实验
- 技术资料
- 抗体英文名:
c-Jun(Phospho-Ser73) Antibody
- 靶点:
c-Jun
- 浓度:
1.0mg/ml
- 应用范围:
WB IHC
- 宿主:
Rabbit
- 适应物种:
Hu Ms Rt
- 克隆性:
Polyclonal
- 保存条件:
Store at -20℃
- 形态:
liquid
- 免疫原:
Peptide sequence around phosphorylation site of serine 73 (L-A-S(p)-P-E) derived from Human c-Jun.
c-Jun(Phospho-Ser73) Antibody
Host Species:
Rabbit
Clonality:
Polyclonal
Purification:
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Applications:
WB IHC
Species Reactivity:
Hu Ms Rt
Specificity:
The antibody detects endogenous level of c-Jun only when phosphorylated at serine 73.
Immunogen Type:
Peptide-KLH
Immunogen Description:
Peptide sequence around phosphorylation site of serine 73 (L-A-S(p)-P-E) derived from Human c-Jun.
Target Name:
c-Jun
Modification:
Phospho
Alternative Names:
AH119; AP1; Jun A; c-Jun; p39
Accession No. :
Swiss-Prot: P05412
NCBI Protein: NP_002219.1
Concentration:
1.0mg/ml
Images:

Western blot analysis of extracts from PC14 cells untreated or treated with EGF using c-Jun(Phospho-Ser73) Antibody #11003.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-Jun(Phospho-Ser73) Antibody #11003(left) or the same antibody preincubated with blocking peptide(right).

Western blot analysis of extracts from C6 cells, treated with PMA or calf intestinal phosphatase (CIP), using c-Jun (Phospho-Ser73) Antibody #11003.
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文献和实验PMID: 23191987
Increase in claudin-2 expression by an EGFR/MEK/ERK/c-Fos pathway in lung adenocarcinoma A549 cells. In Biochim Biophys Acta on 2012 Jun by Akira Ikari, Tomonari Sato, et al..PMID: 22546605, , (2012),
PMID: 22546605
. These residues (Ser 63 and 73) are required to be phosphorylated for efficient transactivation function. The kinases responsible for this modification in vivo are the SAPK/JNKs. These kinases bind with very high affinity to a region in c-Jun termed the delta
secondary antibody review -- data from 99 publications
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