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Active Motif公司是一家致力于研发和生产核细分子生物学和表观遗传学研究用试剂的专业公司，也是世界著名的转录因子试剂生产商和CHIP-seq外包服务供应商。
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文献和实验Purification of Recombinant p53 from Sf9 Insect Cells
We describe a method for purifying recombinant p53 from baculovirus infected cells in one step by anion exchange chromatography. The p53 is full-length with no flanking sequences and its expression is driven by the baculovirus polyhedron
Senescence Regulation by the p53 Protein Family
. Importantly, p53, p63, and p73 are necessary for the maintenance of adult stem cells. Therefore, understanding the dual role the p53 protein family in cancer and aging is critical to solve cancer and longevity in the future. In this chapter, we provide
Proteolysis of p53 Protein by Ubiquitous Calpains
p53 is a key regulator of the cell cycle and apoptosis which is essential for maintenance of genome integrity (1 –4 ). It can function as a transcription factor, but other roles in DNA repair, homologous recombination and the regulation
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