CD56 (NCAM) (123C3) Mouse mAb

价格询价

品牌Cell Signaling Technology
货号
3576
产地USA
更新日期2026年05月28日

应用范围W, IHC-P, IF-IC, F
适应物种H

美国CST中国公司(丁香通商铺)

品牌商

13 年钻石会员

详细信息
文献和实验
技术资料

抗体英文名：
CD56 (NCAM) (123C3) Mouse mAb
抗原：
membrane preparation of a small cell lung carcinoma specimen
应用范围：
W, IHC-P, IF-IC, F
级别：
详见MSDS文件
适应物种：
H
供应商：
CST
保质期：
详见说明书
库存：
大量
是否单克隆：
1
保存条件：
-20°c
规格：
400 ul (100 tests)/carrier free & custom formulation / quantity

规格：		产品价格：	￥请询价
规格：	400 ul (100 tests)	产品价格：	￥请询价
规格：	carrier free & custom formulation / quantity	产品价格：	￥请询价

pathway more info application references datasheet PDF MSDS PDF protocols

Applications Key: W=Western Blotting IHC-P=Immunohistochemistry (Paraffin) IF-IC=Immunofluorescence (Immunocytochemistry) F=Flow Cytometry
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W IHC-P IF-IC F	H	Endogenous	120 to 220	Mouse IgG1

Protocols	3576: Flow , IHC / Paraffin , Immunofluorescence , Western Blotting
Specificity / Sensitivity	CD56 (NCAM) (123C3) Mouse mAb detects endogenous levels of total CD56 protein.
Source / Purification	Monoclonal antibody is produced by immunizing BALB/c mice with a membrane preparation of a small cell lung carcinoma specimen. Western Blotting Western blot analysis of extracts from human cerebellum using CD56 (NCAM) (123C3) Mouse mAb. IHC-P (paraffin) Immunohistochemical analysis of paraffin-embedded human neuroblastoma, using CD56 (NCAM) (123C3) Mouse mAb. Flow Cytometry Flow cytometric analysis of whole blood using CD56 (NCAM) (123C3) Mouse mAb. IF-IC Confocal immunofluorescent analysis of SH-SY5Y cells (left) and HeLa cells (right) using CD56 (NCAM) (123C3) Mouse mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).
Background	NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resulting in different cytoplasmic domains (1). NCAM mediates neuronal attachment, neurite extension and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma and rhabdomyosarcoma (2). CD56 and CD16 are commonly used to identify NK cells although some cells with the T cell markers CD3 and CD4 also express CD56 (3). Cunningham, B. A. et al. (1987) Science 236, 799-806. Seidenfaden, R. et al. (2003) Mol. Cell. Biol. 23, 5908-5918. Robertson, M.J. and Ritz, J. (1990) Blood 76, 2421-2438.
Application References	Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !
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