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文献和实验) is accompanied with or inactivates the GSK activity. However, it is still not conclusive what the role of Tyr phosphorylation (Y216 fro beta, Y279 for alpha) on GSK activity is. One reference is a review paper published in Cell in 2001, you may take a quick
Characterization of Nuclear Receptor Ligands by Multiplexed Peptide Interactions
receptor. Nature 389:753‐758. Glickman, J.F., Wu, X., Mercuri, R., Illy, C., Bowen, B.R., He, Y., and Sills, M. 2002. A comparison of ALPHAScreen, TR‐FRET, and TRF as assay
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
-catenin. FEBS Lett. 458, 247–251. 10. Ding, V. W., Chen, R. H., and McCormick, F. (2000) Differential regulation of glycogensynthase kinase 3beta by insulin and Wnt signaling. J. Biol. Chem. 275, 32475– 32481. 11. Liu, X., Rubin, J. S., and Kimmel, A. R
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