- ￥5300
- GeneTex
- 美国
- GTX50141
- 2025年07月13日
- WB, ICC/IF, IHC-P
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Peptide sequence around phosphorylation site of serine 190 (G-L-S(p)-P-A) derived from human Progesterone Receptor.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX50141
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Rabbit
- 应用范围：
WB, ICC/IF, IHC-P
- 浓度：
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
Progesterone Receptor (phospho Ser190)
- 抗体英文名：
Progesterone Receptor (phospho Ser190) antibody
- 抗体名：
Progesterone Receptor (phospho Ser190) 抗体
- 规格：
100 μl
WB analysis of extracts from SKOV3 cells untreated (lane 1) or treated with EGF (lane 2) using GTX50141 Progesterone Receptor (phospho Ser190) antibody.
ICC/IF analysis of methanol-fixed MCF cells using GTX50141 Progesterone Receptor (phospho Ser190) antibody.
IHC-P analysis of human breast carcinoma tissue using GTX50141 Progesterone Receptor (phospho Ser190) antibody.
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文献和实验Human progesterone receptor (PR) is a member of the nuclear hormone receptor superfamily of transcriptional activators, which share a common modular structure consisting of a C-terminal ligand-binding domain (LBD), a highly conserved
Several assays exist to determine receptor status in ovarian cancers, like radio ligand binding assays, biochemical analysis, and even Northern blotting. However, patholo- gists generally prefer to judge the presence of biological markers
), and causes activation of KOR. Agonist-activated KOR becomes a substrate for G protein receptor kinase (GRK), which phosphorylates the Ser369 residue at the C-terminal tail of the receptor in the first step in the β-Arrestin-dependent desensitization cascade
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