Quantitative Immunohistochemistry of Estrogen and Progesterone Receptor Positivity in Ovarian Tumors: A Rapid and Reliable Stereological Approach
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Several assays exist to determine receptor status in ovarian cancers, like radio ligand binding assays, biochemical analysis, and even Northern blotting. However, patholo- gists generally prefer to judge the presence of biological markers in the context of tissue architecture, using immunohistochemistry (IHC). This allows for a better appreciation of exactly what in a tumor is positive for staining, and what is not.
