重组人 IL-1RA / IL1RN 蛋白(产品说明)
蛋白名称:Human IL-1RA / IL1RN Protein
蛋白构建:A DNA sequence encoding the mature form of human IL1RA isoform1 (NP_776214.1) (Arg 26-Glu 177) was expressed.
表达宿主:E. coli
蛋白纯度:> 97 % as determined by SDS-PAGE
蛋白活性:1. Measured by its binding ability in a functional ELISA. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R2-Fc (Cat:10111-H02H), The EC50 of human IL1R2-Fc (Cat:10111-H02H) is 0.04-0.1 μg/mL.2. Measured by its binding ability in a functional ELISA. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R1-Fc (Cat:10126-H02H), The EC50 of human IL1R1-Fc (Cat:10126-H02H) is 0.08-0.2 μg/mL.3. Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 250pg/mL IL1a. The EC50 for this effect is typically 3-12 ng/mL.
蛋白内毒素:Please contact us for more information.
预测N端:Met
蛋白分子量:The recombinant human IL1RA consists of 153 amino acids and predicts a molecular mass of 17.3 kDa which is also estimated by SDS-PAGE.
蛋白NP号:NP_776214.1
蛋白氨基酸序列:Arg26-Glu177
蛋白标签:Native
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
1, Liu, J; et al. Trelagliptin ameliorates IL-1β-impaired chondrocyte function via the AMPK/SOX-9 pathway. Molecular immunology, Pubmed: 34666245
2, Luo, X; et al. Inflammatory human umbilical cord-derived mesenchymal stem cells promote stem cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner.. BioMed Research International , Pubmed: 29670904