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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Mouse IgG1-Fc Protein (102 Cys/Ser)
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
1.00 mg/100.00 µg/200.00 µg
| 规格: | 1.00 mg | 产品价格: | ¥7600.0 |
|---|---|---|---|
| 规格: | 100.00 µg | 产品价格: | ¥1660.0 |
| 规格: | 200.00 µg | 产品价格: | ¥1790.0 |
蛋白名称:IgG1蛋白, IgG1 protein
蛋白构建:The Fc region of mouse IgG1 (P01868-1) (Val 98-Lys 324) (one aa mutation, 102 Cys / Ser) was expressed and purified.
表达宿主:HEK293 Cells
蛋白纯度:> 95 % as determined by SDS-PAGE
蛋白活性:0
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Val 98
蛋白分子量:The recombinant mouse IgG1 Fc consists of 227 amino acids and has a predicted molecular mass of 25.8 kDa. As a result of glycosylation, the apparent molecular mass of rmFc is approximately 32 kDa in SDS-PAGE under reducing conditions.
蛋白NP号:P01868-1
蛋白氨基酸序列:Val98-Lys324,102Cys/Ser
蛋白标签:Native
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验2, Chi X, et al. Humanized single domain antibodies neutralize SARS-CoV-2 by targeting the spike receptor binding domain.Nature communications, PubMed ID: 32913273
Assessing Fc Glycan Heterogeneity of Therapeutic Recombinant Monoclonal Antibodies Using NP-HPLC
or plants. Glycans present in the Fc region can affect functions of rMAbs. These Fc glycans are heterogeneous and impact binding of rMAbs to Fc gamma receptors (FcγRs) and C1q protein. As a result Fc glycans affect antibody-dependent cellular cytotoxicity
and growth factors derived from mouse Engelbreth–Holm–Swarm �sarcoma cells. The complexity and lot-to-lot variation of Matrigel preparations has prompted the search for more defined substrates that can support pluripotent stem cell culture. A recombinant
ANTIBODY BINDING TO PROTEIN A AND PROTEIN G
A Protein G Human IgG1 ++++ ++++ Human IgG2 ++++ ++++ Human IgG3 - ++++ Human IgG4 ++++ ++++ Mouse IgG1 + ++++ Mouse IgG
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