- ￥3870 - 25190
- Sino Biological
- 北京
- 10707-H02H
- 2026年01月26日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
在-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human EPOR / Erythropoietin Receptor Protein (Fc Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
100 µg/1 mg
| 规格： | 100 µg | 产品价格： | ￥3870.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥25190.0 |
蛋白名称：Human EPOR / Erythropoietin Receptor Protein (Fc Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met-Pro 250) of human erythropoietin receptor (NP_000112.1) precursor was expressed with the C-terminal fused Fc region of human IgG1.
表达宿主：HEK293 Cells
蛋白纯度：> 90 % as determined by SDS-PAGE
蛋白活性：1. Measured by its binding ability in a functional ELISA. Immobilized EPOR (hFc Tag) (Cat:10707-H02H) at 2μg/mL (100μL/well) can bind Cynomolgus Erythropoietin-His (Cat:90133-C08H), the EC50 of Cynomolgus Erythropoietin-His (Cat: 90133-C08H) is 4-20 ng/mL. 2. Measured by its ability to inhibit Epodependent proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is 1-4 ng/ml in the presence of 0.1 U/mL Recombinant Human EPO.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Ala 25
蛋白分子量：The recombinant human EPOR/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The reduced monomer consists of 460 amino acids and has a predicted molecular mass of 51.0 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhEPOR/Fc monomer is approximately 55-60 kDa due to glycosylation.
蛋白NP号：NP_000112.1
蛋白氨基酸序列：Met1-Pro250
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验和分子结构上也有很大的相似性。 （二）造血细胞因子受体超家族 造血细胞因子受体超家族（haemopoietic cytokine receptor superfamily）又称细胞因子受体家族（cytokine receptor family），可分为红细胞生成素受人本超家族（erythropoietin receptor superfamily,ERS）和干扰素受体家族（interferon receptor family。 1.ERSERS所有成员胞膜外区与红细胞
GHR,EPOR,PRLR,G-CSFR Form homodimers IL-3 receptor subfamily IL-3R,GM-CSFR,IL-5R Form complexes with the cβ subunit IL-6 receptor subfamily IL-6R,LIFR,CNTFR,IL-11R Form
【资源】全面归类网址：毕赤酵母表达各种来源蛋白（细菌，真菌，植物，人类等）
-7-receptorS, 6 mg/L, α-MF[224]Dipeptidyl peptidase IV (DP IV)S, 0.5mg/L, active551Double-stranded RNA-specific editase I (hREDI)I, 1 mg/L[225]ElastaseS, α-MF, active403EndostatinS, 20-200 mg/L, α-MF[170, 226, 397Erythropoietin receptor variantS, 200 mg/L439Fas
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