- ￥198 - 2960
- TargetMol
- 美国
- T6649
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
(S)-(+)-Rolipram
- 库存：
10
- 供应商：
TargetMol
- CAS号：
85416-73-5
- 规格：
5 mg/10 mg/1 mg/25 mg/1 mL/50 mg/100 mg
| 规格： | 5 mg | 产品价格： | ￥469.0 |
|---|---|---|---|
| 规格： | 10 mg | 产品价格： | ￥813.0 |
| 规格： | 1 mg | 产品价格： | ￥198.0 |
| 规格： | 25 mg | 产品价格： | ￥1360.0 |
| 规格： | 1 mL | 产品价格： | ￥459.0 |
| 规格： | 50 mg | 产品价格： | ￥1980.0 |
| 规格： | 100 mg | 产品价格： | ￥2960.0 |
Product Introduction
Bioactivity
英文名:(S)-(+)-Rolipram
描述:(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
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文献和实验Enzymatic Synthesis of (S)-Phenylalanine and Related (S)-Amino Acids by Phenylalanine Dehydrogenase
substituents in the reductive amination reaction. Optically pure (S)-phe and other (S)-amino acids are quantitatively synthesized from their oxo-analogs using PheDH, with a regeneration of NADH by formate dehydrogenase from Candida boidinii No. 2201. Acetone
have led to the conclusion that CYP2C19 is a major P450 responsible for (S)-mephenytoin 4’-hydroxylation activity in human liver microsomes (1 , 2 ). This is supported by the finding that cDNA-expressed CYP2C19 has a 50-to lOO-fold greater turnover number
A reverse-phase, high-performance liquid chromatography method is described for the quantification of 4′-hydroxymephenytoin formed enzymatically from 14 C-labeled (S )-mephenytoin following incubation with cDNA-expressed CYP2C19 or human
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