使用浓度:
PMA的具体使用浓度请参考相关文献,并根据自身实验条件(如实验目的,细胞种类,培养特性等)进行摸索和优化。
Phorbol 12-myristate 13-acetate (PMA) is a diester of phorbol and activates the signal transduction enzyme protein kinase C (PKC). It is used as a tumor promoter and to stimulate division of B-cells. With ionomycin, PMA induces the activation of many cell types to produce cytokines.
CAS Number: 16561-29-8
Storage:-20°C.
Synonyms: PMA, TPA, Phorbol ester, croton oil.
Formulation: Crystalline solid
Chemical Name: 12-O-Tetradecanoylphorbol-13-acetate
Molecular Formula: C36H56O8
Molecular Weight:616.8
Purity:≥98%
Description: Phorbol 12-myristate 13-acetate (PMA) is a diester of phorbol and activates the signal transduction enzyme protein kinase C (PKC). It is used as a tumor promoter and to stimulate division of B-cells. With ionomycin, PMA induces the activation of many cell types to produce cytokines.
Preparation and storage: Soluble in organic solvents such as ethanol and DMSO. DMSO up to 100mM..