- ￥2570 - 3220
- Sino Biological
- 北京
- 10755-H20B
- 2026年01月26日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human SRC Kinase / Proto-oncogene c-Src Protein (His & GST Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
20.00 µg/50.00 µg
| 规格： | 20.00 µg | 产品价格： | ￥2570.0 |
|---|---|---|---|
| 规格： | 50.00 µg | 产品价格： | ￥3220.0 |
蛋白名称：Human SRC Kinase / Proto-oncogene c-Src Protein (His & GST Tag)
蛋白构建：A DNA sequence encoding the human SRC (P12931-1) (Met 1-Leu 536) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
表达宿主：Baculovirus-Insect Cells
蛋白纯度：> 90 % as determined by SDS-PAGE
蛋白活性：The specific activity was determined to be ＞80 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Met
蛋白分子量：The recombinant human SRC/GST chimera consists of 773 amino acids and has a calculated molecular mass of 87.7 KDa. It migrates as an approximately 81 KDa band in SDS-PAGE under non-reduced conditions.
蛋白NP号：P12931-1
蛋白氨基酸序列：Met1-Leu536
蛋白标签：N-GST & His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验2, Kim, J; et al. Targeting isoforms of RON kinase (MST1R) drives antitumor efficacy. Cell death and differentiation, PMID: 37926711
3, Hong, S; et al. A non-catalytic role of IPMK is required for PLCγ1 activation in T cell receptor signaling by stabilizing the PLCγ1-Sam68 complex. Cell communication and signaling : CCS, PMID: 39478550
4, Sheng, G; et al. Puerarin Improves Cancer-Induced Bone Pain by Recovering Mitochondrial Dysfunction in the Spinal Cord. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, PMID: 40493135
5, Feng, Y; et al. TBK1 phagosomal recruitment enhances antifungal immunity via positive feedback regulation with SRC. Cell reports, PMID: 40638388
第五节 蛋白激酶C 蛋白激酶C（protein kinase C,PKC）是一类Ca 2+ 、磷脂依赖性的蛋白激酶，在跨膜信号传递过程中起着重要作用。PKC通过催化多种蛋白质上Ser/Thr磷酸化，调节多种细胞的代谢、生长、增殖和分化。 表 8-3 哺乳动物组织内的PKC亚类 亚 类 氨基酸残基 分子量（kDa） 激 活 剂 表达组织 A组：经典PKC
Interfering with Ras Signaling Using Membrane-Permeable Peptides or Drugs
During the last two decades since the first oncogene product called v-Src was identified as a constitutively activated mutant of a normal mitogenic gene (proto-oncogene) encoding a Tyr kinase called c-Src in early 1980s, it was firmly
protein-2 kinase,MAP-2k）及细胞外信号调节的激酶2（extracellular signal-regulated kinase2,ERK2）等。 属于src家族的蛋白酪氨酸激酶是一组膜结合蛋白，包括p60 arc 、p56 lck 、p59 fyn 、p59 yes 、(p62 ues )、p56 lyn 、p59 hck
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