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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Human GDF-15 / GDF15 Protein (His Tag) (Mature Form)
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
1.00 mg/20.00 µg/100.00 µg
| 规格: | 1.00 mg | 产品价格: | ¥19380.0 |
|---|---|---|---|
| 规格: | 20.00 µg | 产品价格: | ¥1580.0 |
| 规格: | 100.00 µg | 产品价格: | ¥3480.0 |
蛋白名称:Human GDF-15 / GDF15 Protein (His Tag) (Mature Form)
蛋白构建:A DNA sequence encoding the mature form of human GDF15 (NP_004855.2) (Ala197-Ile308) was expressed with a polyhistidine tag at the N-terminus.
表达宿主:Yeast
蛋白纯度:> 90 % as determined by SDS-PAGE.
蛋白活性:0
蛋白内毒素:Please contact us for more information.
预测N端:His
蛋白分子量:The recombinant mature form of human GDF15 consists of 122 amino acids and predicts a molecular mass of 13.7 kDa. As a result of glycosylation, it migrates as an approximately 18.2 kDa band in SDS-PAGE under reducing conditions.
蛋白NP号:NP_004855.2
蛋白氨基酸序列:Ala197-Ile308
蛋白标签:N-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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- 作者
- 内容
- 询问日期
文献和实验1 月内连登 4 顶刊,这个炙手可热的明星蛋白 GDF15 到底什么来路?
1 月 9 号,代谢领域顶级期刊 Cell Metabolism 背靠背发表了题为《Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention》1 和《GDF15 Induces Anorexia through Nausea and Emesis》2 两篇长文,分别报道了 GDF15 在一型糖尿病和厌食症中的关键
三句话读懂一篇 CNS:颜宁团队 2023 首个研究成果发表;长期单身,患老年痴呆风险更高
agonist reduces body weight and metabolic disorder in mice and non-human primates。 该研究进行了长效双 GLP-1/GDF15 蛋白的设计和生成,发现了主要候选 GLP-1/GDF15 分子——QL1005,其在肥胖小鼠体内表现出较强的减肥效果,并对其他几种代谢结果进行有益的调节,以及改善药代动力学(PK)参数。 图 6:来源 Cell Metabolism 7. Journal of Hepatology:鉴定肝细胞
Using the scan‐x Web Site to Predict Protein Post‐Translational Modifications
spectrometry data is providing evidence that almost every protein in the cell undergoes some form of post?translational modification. We describe a protocol to use the scan?x Web site to view predicted acetylation sites in the human proteome and predicted
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