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- 详细信息
- 文献和实验
- 技术资料
- 形态:
液态/粉状
- 保存条件:
-20℃保存
- 克隆性:
多克隆
- 标记物:
见说明书
- 适应物种:
人,大鼠,小鼠,兔
- 宿主:
Goat,Rabbit,Mouse
- 应用范围:
科研使用
- 浓度:
1mg/1ml
- 靶点:
来电咨询
- Tubulin (TU-20) Monoclonal Antibody (SIGNET)详细信息:
-
Description 
Monoclonal Antibody against Tubulin (TU-20)
(Formerly Signet Catalog Nos: 840-01, 840-26 L2 Predilute)Intended Use 
**Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone 
TU-20 Form 
Tissue Culture Supernatant (in 0.01M PBS + 0.1% NaN3 + 1% BSA) Host 
Mouse Species Reactivity 
Tubulin (TU-20) Monoclonal Antibody (SIGNET)Human IsoType 
IgG1 Specificity 
Signet’s Tubulin antibody reacts with a neuron specific epitope (ESESQGPK) of the β-III isoform of tubulin.
Concentrated Format:
SIG-3840-1000 [1 mL]
Prediluted Format:
SIG-3840-26 [6 mL] is ready-to-use with Biotin-based detection systems such as Signet’s USA Ultrastreptavidin Detection (SIG-32250).Uses 
This antibody is effective in immunohistochemistry (IHC). Suggested Working Dilution 
The optimal working dilution should be determined for each specific assay condition. - IHC:
Tissue Sections: Formalin-fixed, paraffin-embedded tissues
Pretreatment: For optimal staining, the sections should be digested with an enzyme such as Protease g for 10 minutes at 37°C.
Incubation: 60 minutes at room temperature when using Biotin based detection systems such as Signet’s USA Ultrastreptavidin Detection (SIG-32250).
Notes 
Positive tissue (human): Brain Storage 
Tubulin (TU-20) Monoclonal Antibody (SIGNET)Store between 2-8°C. References 
Legault J, et al. Microtubule disruption induced in vivo by alkylation of beta-tubulin by 1-aryl-3-(2-chloroethyl)ureas, a novel class of soft alkylating agents.Cancer Res 60(4):985-92, 2000.
Bini L, et al. Protein expression profiles in human breast ductal carcinoma and histologically normal tissue. Electrophoresis 18(15)M:2832-41, 1997.
Diaz-Nido J, et al. Phorphorylation of a neuronal specific beta-tubulin isotype. J Biol Chem 265(23):13949-54, 1990.
Katsetos CD, et al. Cerebellar desmoplastic medullablastomas. A further immunohistochemical characterization of a reticulin free pale islands. Arch Pathol Lab Med 113(9):1019-29, 1989.Warranty/Conditions 
Covance products may not be resold or modified for resale without prior written approval. - IHC:
- Tubulin (TU-20) Monoclonal Antibody (SIGNET)
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