- 询价
- R&D
- 美国/中国
- xy-71R
- 2025年07月15日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 文献和实验
- 技术资料
- 形态：
液态/粉状
- 保存条件：
-20℃保存
- 克隆性：
多克隆
- 标记物：
见说明书
- 适应物种：
人，大鼠，小鼠，兔
- 宿主：
Goat，Rabbit，Mouse
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 靶点：
来电咨询
- Rat Blood-Brain Barrier (SMI 71) Monoclonal Antibody保存于运输说明：
- Store at -20°C
- 详细信息：
-
Description 
Monoclonal antibody against Rat Blood-Brain Barrier Clone SMI-71 Form Ascites Fluid (contains 0.01M sodium azide) Host Mouse Species Reactivity Rat IsoType Rat Blood-Brain Barrier (SMI 71) Monoclonal Antibody IgM [Ab] 2 mg/mL Specificity SMI 71 is specific for an endothelial protein found in areas with blood-brain or blood-nerve barriers. The antibody does not react with endothelia of periventricular organs or with fenestrated endothelia in peripheral tissues. Reactivity with the antibody develops in newborn rats along with maturation of the blood brain barrier. Reactivity disappears in lesions of experimental allergic encephalomyelitis. Contrary to the belief that astrocytes and perhaps neurons are essential for the establishment of the blood-brain barrier, destruction of neurons (monitored by SMI 311 and anti- MAP2) and of astrocytes (monitored by anti-GFAP and anti-S-100) leads only to transient abolition of SMI 71 reactivity and only transient transendothelial passage of serum albumin. This antibody is species-specific for rat only. No specific reaction has been found on Western blots of denaturing and non-denaturing gels. Uses This antibody is effective in immunocytochemistry and ELISA applications. Suggested Working Dilution The extent of permissible dilution of SMI 71 beyond those recommended for general application depends upon nature and concentration of the antigen examined, species of the antigen, method of fixation and kind of section examined. This antibody is sold for laboratory research use only, not for human or in-vivo use. Covance antibodies may not be resold or modified for resale without prior written approval. - Immunohistochemistry: 1:1,000
- ELISA: 1:1,000
Tissue Preparation: SMI 71 reacts on paraffin, vibratome and frozen tissue sections. Tissues can be fixed in a variety of paraformaldehyde, formaldehyde or glutaraldehyde-containing fixativesStorage Rat Blood-Brain Barrier (SMI 71) Monoclonal Antibody Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. References Ghabriel MN, Lu JJ, Hermanis G, Zhu C, Setchell BP. Expression of a blood-brain barrier-specific antigen in the reproductive tract of the male rat. Reproduction 123:389-397, 2002.
Hanu R, McKenna M, ONeill A, Resneck WG, Bloch RJ. Monocarboxylic acid transporters, MCT1 and MCT2, in cortical astrocytes in vitro and in vivo. Am. J. Physiol. Cell Physiol. 278:921 - 930, 2000.
Sternberger NH, Sternberger LA, Kies MW, Shear CR. Cell surface endothelial proteins altered in experimental allergic encephalomyelitis. J Neuroimmunol 21:241, 1989.
Sternberger NH, Sternberger LA: Blood-brain barrier protein recognized by monoclonal antibody. Proc. Natl. Acad. Sci. USA 84:8169, 1987.
Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - Rat Blood-Brain Barrier (SMI 71) Monoclonal Antibody
- xy-1256xy FGF4/HSTF1/HBGF-4(Fibroblast Growth Factor4)纤维母细胞生长因子4抗原
xy-1257xy FGF5 peptide纤维母细胞生长因子5抗原
xy-0809xy Fibulin 1衰老关键蛋白抗原
xy-1170xy FOS BFosB抗原
xy-1188xy FRA2/FOSL2(Fos related/like antigen 2)FOS样抗原2
xy-2585xy FOXF1(Forkhead box protein F1)叉头蛋白F1抗原
xy-1775xy FOXJ1/HFH-4 peptide插头蛋白J1抗原
xy-1275xy FoxP1(Forkhead box P1)FoxP1（T细胞转录因子）抗原
xy-2687xy FOXM1/HFH 11 peptide插头蛋白M1抗原
xy-0886xy Measles virus of fusion protein麻疹病毒抗原（麻疹病毒融合蛋白）
xy-0895xy FSH-R(Follicle-stimulating hormone receptor precursor)促卵泡刺激素受体抗原
xy-1536xy FSH(Follicle-stimulating hormone precursor)促卵泡刺激素抗原
xy-1232xy GABRA1(gamma-aminobutyric acid (GABA) A receptor, alpha 1)γ1氨基丁酸A型受体α1抗原
xy-0533xy GABAB1(GABAb Receptor 1)g-氨基丁酸B1受体(多肽)
xy-1293xy GABABR2/GB2(GABA B Receptor 2)γ1氨基丁酸A型受体B2抗原
xy-1302xy GAD-67 (glutamate decarboxylase 67)谷氨酸脱羧酶-67抗原
xy-1361xy GADD153(Growth arrest and DNA damage-inducible 153)生长抑制DNA损伤基因153抗原
xy-1641xy phospho GAP-43(pSer41)(phospho Growth associated protein 43 )磷酸化神经生长相关蛋白43抗原
xy-0834xy GAPDH3-磷酸甘油醛脱氢酶(人)抗原
xy-2209xy CXCR3/CD183 peptide细胞表面趋化因子受体3抗原
xy-1452xy GATA-3(GATA binding factor 3)GATA结合蛋白3抗原
xy-1778xy GATA-4(GATA binding factor 4)GATA结合蛋白4抗原
xy-1250xy Gax(growth arrest-specific homeobox)生长终止特异性同源盒基因抗原
xy-1288xy GDF8/MSTN(growth differntiation factor 8)生长分化因子8抗原
xy-1024xy GDNF (Glial cell line-derived neurotrphic factor)胶质细胞源性神经营养因子抗原
xy-1160xy Gelsolin凝溶胶蛋白抗原
xy-0844xy GFP绿色荧光蛋白
xy-0890xy GFP绿色荧光蛋白
xy-1173xy GITR (glucocorticoidinduced tumor necrosis factor receptor)糖皮质激素诱导肿瘤坏死因子受体抗原
xy-1206xy GLI1(GLI-Kruppel family member 1)下游转录因子Gli1蛋白抗原
xy-0933xy GLP-1/KG-31(Glucagon-like peptide-1) peptide胰高血糖素样肽-1（多肽）
xy-0085xy GLP-1 peptide胰高血糖素样肽-1（多肽）
xy-1207xy GLUT3(Glucose transporter 3)葡萄糖转运蛋白3抗原
xy-0999xy GM-CSF(Granulocyte-Macrophage Colony Stimulating Factors)粒细胞-巨噬细胞克隆刺激因子抗原
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Rat Blood-Brain Barrier (SMI 71) Monoclonal Antibody
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