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R&D Systems货号DEP00人促红细胞生成素IVD
ELISA试剂盒(Human Erythropoietin Quantikine IVD ELISA Kit)上海睿安生物13611631389- ￥11295.38
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
2-8°C
- 保质期：
1年
- 英文名：
Human Erythropoietin Quantikine IVD ELISA Kit
- 库存：
100⁺盒
- 供应商：
上海睿安生物13611631389
- 规格：
1Kit/套/盒
R&D Systems货号DEP00人促红细胞生成素IVD ELISA试剂盒(Human Erythropoietin Quantikine IVD ELISA Kit)上海睿安生物13611631389
Human Erythropoietin Quantikine IVD ELISA Kit
Background:Erythropoietin/EPO
Erythropoietin (Epo), a glycoprotein (~30,400 Daltons) produced primarily by the kidney, is the principal factor regulating red blood cell production (erythropoiesis) in mammals. Renal production of Epo is regulated by changes in oxygen availability. Under conditions of hypoxia, the level of Epo in the circulation increases and this leads to increased production of red blood cells.
The over-expression of Epo may be associated with certain pathophysiological conditions (1, 2). Polycythemia exists when there is an overproduction of red blood cells (RBCs). Primary polycythemias, such as polycythemia vera, are caused by Epo-independent growth of erythrocytic progenitors from abnormal stem cells and low to normal levels of Epo are found in the serum of affected patients. On the other hand, various types of secondary polycythemias are associated with the production of higher than normal levels of Epo. The overproduction of Epo may be an adaptive response associated with conditions that produce tissue hypoxia, such as living at high altitude, chronic obstructive pulmonary disease, cyanotic heart disease, sleep apnea, high-affinity hemoglobinopathy, smoking, or localized renal hypoxia (1, 2). In other instances, excessive Epo levels are the result of production by neoplastic cells. Cases of increased Epo production and erythrocytosis have been reported for patients with renal carcinomas (3), benign renal tumors (4), Wilms' tumors, hepatomas (5), liver carcinomas (6), cerebellar hemangioblastomas (3, 7, 8), adrenal gland tumors (9), smooth muscle tumors (3, 9), and leiomyomas (10).
Deficient Epo production is found in conjunction with certain forms of anemias. These include anemia of renal failure and end-stage renal disease (1, 2, 11), anemias of chronic disorders [chronic infections (1), autoimmune diseases (1), rheumatoid arthritis (12), AIDS (13), malignancies (14)], anemia of prematurity (2), anemia of hypothyroidism (2), and anemia of malnutrition (2). Many of these conditions are associated with the generation of IL-1 and TNF-alpha, factors that have been shown to be inhibitors of Epo activity (1, 15). Other forms of anemias, on the other hand, are due to Epo-independent causes and affected individuals show elevated levels of Epo (2). These forms include aplastic anemias, iron deficiency anemias, thalassemias, megaloblastic anemias, pure red cell aplasias, and myelodysplastic syndromes.
Entrez Gene IDs:2056(Human);13856(Mouse);24335(Rat)
Alternate Names:ECYT5;EP;EPO;epoetin;Erythropoietin;MGC138142;MVCD2
睿安公司专业技术服务
荧光定量PCR、甲基化检测、文库构建、原核和真核蛋白表达、高通量测序、抗体定制服务、WB检测、IHC检测。
睿安公司代理及优势品牌：
免疫学 ：Abgent、CST、R&D、Abcam、BD、Epitomics、Santa cruz、Jackson
耗材类 ： Ammex、Fisher、Bioplastics、Axygen、Corning、Greiner，Nunc-Nalgene
分子和细胞 ：Fermentas、hyclone-pierce、Qiagen、Bio-Rad
综合类 ： Sigma、 MERCK、Millipore、Roche、Invitrogen
自主品牌 ：Rainbio 生化类：Sigma-Vetec 、 MP
肥胖代谢类 ：Biovendor、ALPCO
表观遗传 ：Zymo ACTIVE MOTIF 神经和信号传导 ：Tocris
其他类 ： Biovision、Biocolor、Covance、Cytoskeleton、ebioscience、GE、Genetex、Invivogen、Omega、
Proteintech 、Socorex 、Vector
一、╳※试剂※╳:
常规血清优势供应:VivaCell货号C04001-500血清、Gemini货号900-108血清、Gemini血清、Gibco血清(10099-141澳洲血清、10270-106南美血清、16000-044血清)、BI血清BI货号04-001-1ACS、Sigma货号F8318-500ml澳洲胎牛血清、Sigma货号F8687澳洲胎牛血清、Sigma货号F2442-500ml特级胎牛血清、ScienCell货号0500澳洲胎牛血清、Cegrogen货号A0500-3010胎牛血清、Cegrogen货号B0500-5010新生牛血清、康源血清
培养基(包括无血清)、冻存液(包括无血清)，包括:友康Yocon
Merck(Millipore/Sigma/Roche/KaPa/Supelco/Avanti/Corning/Brand)正式授权代理、博奥龙Biodragon独家总代理、EFL独家总代理、碧云天Beyotime代理
☆☆☆☆☆☆Beckman货号A63881纯化磁珠Agencourt AMPure XP(60ml/瓶)/A63882(450ml/瓶)；Beckman货号B23317核酸片段筛选试剂盒Agencourt SPRIselect(5ml/瓶)
分子类:Biotium货号41003的GelRed染料、货号31000的EvaGreen染料、Zymo Research、Qiagen
饲料类:Research Diets、Dyets
二、╳※耗材※╳:
洁特JET耗材(各类常规用实验耗材)、赛普Cellpro耗材/KirGen耗材、博麦迪(常规的)各类试剂瓶
Bioplastics
Thermo Fisher Scientific的很多产品线，包括旗下的:
一、Nunc耗材
二、QSP耗材(各类吸头/滤芯吸头、离心管、PCR管等)
三、Nalgene耗材仪器
四、FisherBrand耗材仪器(含各类盖玻片载玻片等)
五、Lab_Serv耗材仪器
六、Finnpipette移液器(如：F1系列、F2系列、F3系列等等各类型号的移液器)
七、Abgene耗材
畅销款:我们是常备有大量现货的
※╳√√✓✔√✓✔√✓✔上海睿安生物科技有限公司成立于2009年，专注于为生命科学和生物技术领域的客户提供优质的产品与服务。代理了多家欧美知名品牌，如美国Thermo Fisher耗材(包括旗下Nunc、QSP、Nalgene、FisherBrand、Lab_Serv耗材仪器、Finnpipette移液器、Abgene耗材，等等)、默克Merck-Millipore/Sigma/Roche/KaPa/Supelco/Avanti/Corning/Brand)、Zymo Research、洁特JET耗材(各类常规用实验耗材)、赛普Cellpro耗材、博奥龙Biodragon独家总代理、EFL独家总代理、碧云天Beyotime代理、Eppendorf、友康Yocon、Research Diets高脂饲料，IBL、BioVendor、Mercodia、ShiBayaji代谢类产品、Axygen-Corning长期大量耗材备货、BioCaot畅销款长期备货，VivaCell血清、Gemini血清、Gibco血清，BI血清现货、ScienCell血清、Sigma血清、Moregate血清、Cegrogen血清、Pierce发光试剂、Fermentas、Invitrogen、Abcam、CST、BD、SAB、R&D systems、Beckman、Qiagen、BD Pharmingen、Biolegend、Jackson、Miltenyi、MP Biomedicals、Biotium更好的荧光试剂产品等品牌。睿安生物始终将“提供更好的产品和服务”作为企业发展的目标和努力的方向，并将通过优质的售前与售后服务，始终如一地为客户提供高质量的产品和服务，我们也希望能得到相关领域中更多老师和同仁们的指导和鞭策，为共创优秀品牌而努力奋斗！询订╳直线13611631389微信号
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文献和实验该产品被引用文献
R&D Systems货号DEP00人促红细胞生成素IVD ELISA试剂盒(Human Erythropoietin Quantikine IVD ELISA Kit)上海睿安生物13611631389
Human Erythropoietin Quantikine IVD ELISA Kit
Background:Erythropoietin/EPO
Erythropoietin (Epo), a glycoprotein (~30,400 Daltons) produced primarily by the kidney, is the principal factor regulating red blood cell production (erythropoiesis) in mammals. Renal production of Epo is regulated by changes in oxygen availability. Under conditions of hypoxia, the level of Epo in the circulation increases and this leads to increased production of red blood cells.
The over-expression of Epo may be associated with certain pathophysiological conditions (1, 2). Polycythemia exists when there is an overproduction of red blood cells (RBCs). Primary polycythemias, such as polycythemia vera, are caused by Epo-independent growth of erythrocytic progenitors from abnormal stem cells and low to normal levels of Epo are found in the serum of affected patients. On the other hand, various types of secondary polycythemias are associated with the production of higher than normal levels of Epo. The overproduction of Epo may be an adaptive response associated with conditions that produce tissue hypoxia, such as living at high altitude, chronic obstructive pulmonary disease, cyanotic heart disease, sleep apnea, high-affinity hemoglobinopathy, smoking, or localized renal hypoxia (1, 2). In other instances, excessive Epo levels are the result of production by neoplastic cells. Cases of increased Epo production and erythrocytosis have been reported for patients with renal carcinomas (3), benign renal tumors (4), Wilms' tumors, hepatomas (5), liver carcinomas (6), cerebellar hemangioblastomas (3, 7, 8), adrenal gland tumors (9), smooth muscle tumors (3, 9), and leiomyomas (10).
Deficient Epo production is found in conjunction with certain forms of anemias. These include anemia of renal failure and end-stage renal disease (1, 2, 11), anemias of chronic disorders [chronic infections (1), autoimmune diseases (1), rheumatoid arthritis (12), AIDS (13), malignancies (14)], anemia of prematurity (2), anemia of hypothyroidism (2), and anemia of malnutrition (2). Many of these conditions are associated with the generation of IL-1 and TNF-alpha, factors that have been shown to be inhibitors of Epo activity (1, 15). Other forms of anemias, on the other hand, are due to Epo-independent causes and affected individuals show elevated levels of Epo (2). These forms include aplastic anemias, iron deficiency anemias, thalassemias, megaloblastic anemias, pure red cell aplasias, and myelodysplastic syndromes.
Entrez Gene IDs:2056(Human);13856(Mouse);24335(Rat)
Alternate Names:ECYT5;EP;EPO;epoetin;Erythropoietin;MGC138142;MVCD2
睿安公司专业技术服务
荧光定量PCR、甲基化检测、文库构建、原核和真核蛋白表达、高通量测序、抗体定制服务、WB检测、IHC检测。
睿安公司代理及优势品牌：
免疫学 ：Abgent、CST、R&D、Abcam、BD、Epitomics、Santa cruz、Jackson
耗材类 ： Ammex、Fisher、Bioplastics、Axygen、Corning、Greiner，Nunc-Nalgene
分子和细胞 ：Fermentas、hyclone-pierce、Qiagen、Bio-Rad
综合类 ： Sigma、 MERCK、Millipore、Roche、Invitrogen
自主品牌 ：Rainbio 生化类：Sigma-Vetec 、 MP
肥胖代谢类 ：Biovendor、ALPCO
表观遗传 ：Zymo ACTIVE MOTIF 神经和信号传导 ：Tocris
其他类 ： Biovision、Biocolor、Covance、Cytoskeleton、ebioscience、GE、Genetex、Invivogen、Omega、
Proteintech 、Socorex 、Vector
一、╳※试剂※╳:
常规血清优势供应:VivaCell货号C04001-500血清、Gemini货号900-108血清、Gemini血清、Gibco血清(10099-141澳洲血清、10270-106南美血清、16000-044血清)、BI血清BI货号04-001-1ACS、Sigma货号F8318-500ml澳洲胎牛血清、Sigma货号F8687澳洲胎牛血清、Sigma货号F2442-500ml特级胎牛血清、ScienCell货号0500澳洲胎牛血清、Cegrogen货号A0500-3010胎牛血清、Cegrogen货号B0500-5010新生牛血清、康源血清
培养基(包括无血清)、冻存液(包括无血清)，包括:友康Yocon
Merck(Millipore/Sigma/Roche/KaPa/Supelco/Avanti/Corning/Brand)正式授权代理、博奥龙Biodragon独家总代理、EFL独家总代理、碧云天Beyotime代理
☆☆☆☆☆☆Beckman货号A63881纯化磁珠Agencourt AMPure XP(60ml/瓶)/A63882(450ml/瓶)；Beckman货号B23317核酸片段筛选试剂盒Agencourt SPRIselect(5ml/瓶)
分子类:Biotium货号41003的GelRed染料、货号31000的EvaGreen染料、Zymo Research、Qiagen
饲料类:Research Diets、Dyets
二、╳※耗材※╳:
洁特JET耗材(各类常规用实验耗材)、赛普Cellpro耗材/KirGen耗材、博麦迪(常规的)各类试剂瓶
Bioplastics
Thermo Fisher Scientific的很多产品线，包括旗下的:
一、Nunc耗材
二、QSP耗材(各类吸头/滤芯吸头、离心管、PCR管等)
三、Nalgene耗材仪器
四、FisherBrand耗材仪器(含各类盖玻片载玻片等)
五、Lab_Serv耗材仪器
六、Finnpipette移液器(如：F1系列、F2系列、F3系列等等各类型号的移液器)
七、Abgene耗材
畅销款:我们是常备有大量现货的
※╳√√✓✔√✓✔√✓✔上海睿安生物科技有限公司成立于2009年，专注于为生命科学和生物技术领域的客户提供优质的产品与服务。代理了多家欧美知名品牌，如美国Thermo Fisher耗材(包括旗下Nunc、QSP、Nalgene、FisherBrand、Lab_Serv耗材仪器、Finnpipette移液器、Abgene耗材，等等)、默克Merck-Millipore/Sigma/Roche/KaPa/Supelco/Avanti/Corning/Brand)、Zymo Research、洁特JET耗材(各类常规用实验耗材)、赛普Cellpro耗材、博奥龙Biodragon独家总代理、EFL独家总代理、碧云天Beyotime代理、Eppendorf、友康Yocon、Research Diets高脂饲料，IBL、BioVendor、Mercodia、ShiBayaji代谢类产品、Axygen-Corning长期大量耗材备货、BioCaot畅销款长期备货，VivaCell血清、Gemini血清、Gibco血清，BI血清现货、ScienCell血清、Sigma血清、Moregate血清、Cegrogen血清、Pierce发光试剂、Fermentas、Invitrogen、Abcam、CST、BD、SAB、R&D systems、Beckman、Qiagen、BD Pharmingen、Biolegend、Jackson、Miltenyi、MP Biomedicals、Biotium更好的荧光试剂产品等品牌。睿安生物始终将“提供更好的产品和服务”作为企业发展的目标和努力的方向，并将通过优质的售前与售后服务，始终如一地为客户提供高质量的产品和服务，我们也希望能得到相关领域中更多老师和同仁们的指导和鞭策，为共创优秀品牌而努力奋斗！询订╳直线13611631389微信号
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芯片产品后续产品简单介绍 在用蛋白芯片进行筛选之后，您还可以用R&D Systems可靠的Quantikine ELISA试剂盒来量化您的结果，而更多的抗体将为深入研究提供更丰富的资源（探索蛋白的奥秘，R&D Systems伴您每一步！)。 七、R&D Systems蛋白芯片文献库： 1、使用R&D Systems Human Phospho-Kinase Array（ARY003）蛋白芯片 Science文献。 A、《科学》焦点文章：癌症治疗新发现－使用R&D蛋白芯片的SCIENCE文章
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文献支持
R&D Systems货号DEP00人促红细胞生成素IVD ELISA试剂盒(Human Erythropoietin Quantikine IVD ELISA Kit)上海睿安生物13611631389
￥11295.38
