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- 详细信息
- 技术资料
- 保存条件：
4℃保存
- 保质期：
6个月
- 英文名：
Drosophila HP1 Polyclonal Antibody
- 库存：
1
- 供应商：
上海信裕
- Drosophila HP1 Polyclonal Antibody保存于运输说明：
- Store at -20°C
- 详细信息：
-
Description 
Polyclonal Antibody against Drosophila HP1 Form Antiserum Host Rabbit Species Reactivity Drosophila HP1 Polyclonal Antibody Drosophila Specificity The Drosophila HP1 protein, product of the Su(var)2-5 locus, is a dose-dependent regulator of gene silencing. HP1 interacts with compacted chromatin (heterochromatin) via its chromodomain (CD). HP1 antisera staining of polytene chromosomes decorates pericentric heterochromaticn and a banded heterochromatic pattern on the small 4th chromosome. The HP1 protein is also known to interact with a number of transcriptional regulators via its chromoshadow domain (CSD), suggesting that HP1 is a bridging factor that couples particular chromatin structures with effects on gene expression. This antibody was raised the peptide sequence, YAVEKIIDRRVRKGKVEYYLKWKG, corresponding to amino acids 24-47 of the Drosophila HP1 protein within the chromodomain (CD) of HP1. It has been shown to specifically stain Drosophila polytene chromosomes. Uses This antibody is effective in immunostaining. Suggested Working Dilution Drosophila HP1 Polyclonal Antibody The optimal working dilution should be determined for each specific assay condition. This antibody is sold for laboratory research use only, not for human or in-vivo use. Covance antibodies may not be resold or modified for resale without prior written approval. - Immunostaining: 1:200
Storage Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. For long-term storage, keep the antibody at -80°C. References Eissenberg JC, Elgin SC. The HP1 protein family: getting a grip on chromatin. Curr. Opin. Genet. Dev. 10(2):204-210, 2000.
Cryderman DE, Morris EJ, Biessmann H, Elgin SC, Wallrath LL. Silencing at Drosophila telomeres: nuclear organization and chromatin structure play critical roles. EMBO J. 18:3724-3735, 1999.Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. Rev. Date 1/1/2004 Drosophila HP1 Polyclonal Antibody - xy-9755R ANKRD26锚蛋白重复结构域蛋白26抗体
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Drosophila HP1 Polyclonal Antibody
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