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Sigma货号P21005-100g现货4-苯基丁酸(4-p

henybutyric acid)上海睿安生物13611631389
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  • ¥1878.65
  • Sigma-Aldrich
  • made in USA
  • P21005-100g
  • 2025年10月20日
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 保存条件

      Room Temperature

    • 保质期

      1年

    • 英文名

      4-phenybutyric acid

    • 库存

      100⁺瓶

    • 供应商

      上海睿安生物13611631389

    • CAS号

      1821-12-1

    • 规格

      100g/瓶

    Sigma货号P21005-100g现货4-苯基丁酸(4-phenybutyric acid)上海睿安生物13611631389

    4-苯基丁酸

    99%

    别名:γ-苯基丁酸,ψ-苯基丁酸,4-苯基丁酸,4-苯基正丁酸,苯丁酸

    产品细节图片1

    说明

    一般描述

    4-苯丁酸(4-PBA)可用于治疗尿素循环代谢障碍。

    应用

    4-PBA已被用作内质网应激(ERS)的选择性抑制剂。
    还可用作合成以下物质的反应剂:
    • 使用路易斯酸催化剂的1-四氢萘酮。
    • 4,N-二苯基丁酰胺。

    产品细节图片2

    同行评审论文(部分文献)

    The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis.
    Kolb PS, et al.
    The International Journal of Biochemistry & Cell Biology, 61, 45-52 (2015)
    Induction of apoptosis coupled to endoplasmic reticulum stress through regulation of CHOP and JNK in bone marrow mesenchymal stem cells from patients with systemic lupus erythematosus
    Guo G, et al.
    Journal of immunology research (2015)
    Endoplasmic Reticulum Stress Induces MUC5AC and MUC5B Expression in Human Nasal Airway Epithelial Cells.
    Min Han Kim et al.
    Clinical and experimental otorhinolaryngology, 12(2), 181-189 (2018-10-20)
    Endoplasmic reticulum (ER) stress is known to be associated with inflammatory airway diseases, and three major transmembrane receptors: double-stranded RNA-activated protein kinase-like ER kinase, inositol requiring enzyme 1, and activating transcription factor 6 (ATF6) play important roles in ER stress-related
    Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway.
    Yu-Yang Ma et al.
    Acta pharmacologica Sinica, 41(3), 404-414 (2019-11-09)
    Xanthatin is a natural sesquiterpene lactone purified from Xanthium strumarium L., which has shown prominent antitumor activity against a variety of cancer cells. In the current study, we investigated the effect of xanthatin on the growth of glioma cells in
    Synthesis of 1-tetralones by intramolecular Friedel?Crafts reaction of 4-arylbutyric acids using Lewis acid catalysts
    Cui DM, et al.
    Tetrahedron Letters, 44(21), 4007-4010 (2003)
    产品细节图片3产品细节图片4产品细节图片5产品细节图片6

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    • 作者
    • 内容
    • 询问日期
    图标文献和实验
    该产品被引用文献

    Sigma货号P21005-100g现货4-苯基丁酸(4-phenybutyric acid)上海睿安生物13611631389

    4-苯基丁酸

    99%

    别名:γ-苯基丁酸,ψ-苯基丁酸,4-苯基丁酸,4-苯基正丁酸,苯丁酸

    引用文献图片1

    说明

    一般描述

    4-苯丁酸(4-PBA)可用于治疗尿素循环代谢障碍。

    应用

    4-PBA已被用作内质网应激(ERS)的选择性抑制剂。
    还可用作合成以下物质的反应剂:
    • 使用路易斯酸催化剂的1-四氢萘酮。
    • 4,N-二苯基丁酰胺。

    引用文献图片2

    同行评审论文(部分文献)

    The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis.
    Kolb PS, et al.
    The International Journal of Biochemistry & Cell Biology, 61, 45-52 (2015)
    Induction of apoptosis coupled to endoplasmic reticulum stress through regulation of CHOP and JNK in bone marrow mesenchymal stem cells from patients with systemic lupus erythematosus
    Guo G, et al.
    Journal of immunology research (2015)
    Endoplasmic Reticulum Stress Induces MUC5AC and MUC5B Expression in Human Nasal Airway Epithelial Cells.
    Min Han Kim et al.
    Clinical and experimental otorhinolaryngology, 12(2), 181-189 (2018-10-20)
    Endoplasmic reticulum (ER) stress is known to be associated with inflammatory airway diseases, and three major transmembrane receptors: double-stranded RNA-activated protein kinase-like ER kinase, inositol requiring enzyme 1, and activating transcription factor 6 (ATF6) play important roles in ER stress-related
    Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway.
    Yu-Yang Ma et al.
    Acta pharmacologica Sinica, 41(3), 404-414 (2019-11-09)
    Xanthatin is a natural sesquiterpene lactone purified from Xanthium strumarium L., which has shown prominent antitumor activity against a variety of cancer cells. In the current study, we investigated the effect of xanthatin on the growth of glioma cells in
    Synthesis of 1-tetralones by intramolecular Friedel?Crafts reaction of 4-arylbutyric acids using Lewis acid catalysts
    Cui DM, et al.
    Tetrahedron Letters, 44(21), 4007-4010 (2003)
    引用文献图片3引用文献图片4引用文献图片5引用文献图片6
    相关实验
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    Sigma货号P21005-100g现货4-苯基丁酸(4-phenybutyric acid)上海睿安生物13611631389
    ¥1878.65