万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
常温,避光
- 克隆性:
单克隆
- 抗体名:
FXI / F11 / Factor XI抗体
免疫原 :
Recombinant human FXI protein ( Catalog#10302-H08H )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant human Factor XI ( rh Factor XI ; Catalog#10302-H08H ; NP_000119.1 ; Met 1- Val 625 ). Factor XI specific IgG was purified by human Factor XI affinity chromatography.
FXI / F11 / Factor XI抗体Background
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the presence of calcium ions. The factor XI is synthesized in the liver as a single polypeptide chain with a molecular weight estimated between 125 ~160 kDa and then is processed into a disulfide-bond linked homodimer. Factor XI is is converted to an active protease, factor XIa, by factor XIIa ( or factor XII) in the presence of high molecular weight kininogen (HMWK) and a polyanionic surface. After the activation reaction, Factor XIa is composed of two heavy and two light chains held together by three disulfide bonds. The heavy chains are derived from the amino termini of the zymogen and responsible for the binding of factor XI to high molecular weight kininogen and for the activation of factor IX, while the light chain contains the catalytic portion of the enzyme and is homologous to the trypsin family of serine proteases. FXI deficiency is a disorder characterized by a mild or no bleeding tendency. The vast majority of the FXI defici
FXI / F11 / Factor XI抗体相关产品如下:
hz-8998R ORC1L起始识别复合蛋白亚基1抗体
hz-6236R OTUB泛素特异性蛋白酶Otubain2抗体
hz-11469R Oligophrenin 1精神发育迟滞相关蛋白Oligophrenin-1抗体
hz-8404R OGFOD2末端多聚腺苷酸2蛋白抗体
hz-6559R ORAV1口腔癌高表达的蛋白1抗体
hz-6560R ORP4氧化固醇结合蛋白4抗体
hz-6558R OLFM4抗细胞凋亡蛋白OLFM44抗体
hz-6556R OCC1结肠癌过度表达蛋白1抗体
hz-6557R OCIAD2卵巢癌免疫反应抗原抗体
hz-5714R OVCA1卵巢癌相关基因1抗体
hz-5723R OSGIN1氧化应激诱导生长抑制因子1抗体
hz-6334R ORP8氧化固醇结合蛋白8抗体
hz-11229R OTUB1泛素特异性蛋白酶OTB1抗体
hz-11764R OPA1视神经萎缩相关蛋白1抗体
hz-15593R OAZ1鸟氨酸脱羧酶抗酶1抗体
hz-11626R OR5T1嗅觉受体家族5亚基1抗体
hz-1111R Oct-3/Oct-4胚胎干细胞关键蛋白抗体
hz-0974R Oxytetracycline土霉素抗体
hz-9750R ANKRD45肿瘤/睾丸抗原117
hz-15594R OAZ2鸟氨酸脱羧酶抗酶2抗体
hz-15595R OAZ3鸟氨酸脱羧酶抗酶3抗体
hz-11520R Orexin Prepro食欲素前体蛋白OX抗体
hz-7025R Otoraplin纤维细胞源性蛋白
hz-6724R OTC鸟氨酸氨基甲酰转移酶抗体
hz-5901R OS9OS-9蛋白抗体
hz-4147R Cenexin1精子尾部结构蛋白抗体
hz-5530R phospho-ODF2(Ser796)磷酸化精子尾部结构蛋白抗体
hz-3687R OGG18-羟基鸟嘌呤DNA糖基化酶
hz-11629R OR10J3嗅觉受体家族10亚基J3抗体
hz-11624R OR2A4嗅觉受体家族2亚基4抗体
hz-11628R OR5P3嗅觉受体家族5亚基3抗体
hz-9369R ODF3B外致密纤维蛋白3B抗体
hz-4917R Osteocalcin骨钙蛋白/骨钙素抗体
hz-9061R ODZ3固生蛋白3抗体
hz-9406R CT135肿瘤/睾丸抗原135抗体
hz-9407R OIF骨诱导因子抗体
hz-11203R OCT6八聚体结合转录因子6抗体
hz-11194R OLIG2少突胶质细胞转录因子2抗体
hz-0807R Os05g0477200 protein水稻白叶枯病菌Os05g0477200蛋白抗体
hz-8506R OSTM1骨硬化病相关跨膜蛋白1抗体
hz-9915R Orosomucoid 2类粘蛋白2抗体
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Molecular Analysis in Factor XI Deficiency
Factor XI (FXI) is the zymogen precursor of an active serine protease that participates in the contact phase of coagulation. Synthesized in the liver, it circulates in the plasma in a noncovalent complex with high molecular weight kininogen
人转录因子E2F1 ( E2F1 )ELISA 试剂盒 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 E2F1 单抗包被于酶标板上,标准品和样品中的 E2F1与单抗结合,加入生物素化的抗人 E2F1 ,形成免疫复合物连接在板上,辣根过氧化物酶标记的 Streptavidin 与生物素结合,加入底物工作液显蓝色,最后加终止液硫酸,在 450nm 处测 OD 值,E2F1 浓度与 OD 值成正比
X性联无丙种球蛋白血症(X-linked agammagl,bulinemia,XLA)是临床上首次确定的体液免疫缺陷病,由Brutor于1952年报道,故又称Bruton病。XLA作为常见的原发性免疫缺陷病之一,特点为血清中各类免疫球蛋白缺乏,或只能测得微量的抗体。外周血和淋巴组织中B细胞减少或完全缺乏,淋巴结中无生发中心和浆细胞。本病起病早,在出生数月后当患儿体内的母源性抗体水平下降时开始发病。临床表现为反复化脓性感染,患者细胞免疫功能不受影响(部分患者有T细胞数量减少),主要缺陷
技术资料暂无技术资料 索取技术资料




