Carboxypeptidase B2 / CPB2抗体

Carboxypeptidase B2 / CPB2抗体产品信息

免疫原 :
Recombinant Human Carboxypeptidase B2 / CPB2 protein (Catalog#11504-H08H)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Human Carboxypeptidase B2 / CPB2 (rh Carboxypeptidase B2 / CPB2; Catalog#11504-H08H; NP_001863.2; Met1-Val423). Carboxypeptidase B2 / CPB2 specific IgG was purified by Human Carboxypeptidase B2 / CPB2 affinity chromatography.
Carboxypeptidase B2 / CPB2抗体 Background
Carboxypeptidase B2, also known as Carboxypeptidase U, Thrombin-activable fibrinolysis inhibitor, Plasma carboxypeptidase B, CPB2, is a secreted protein which belongs to the peptidase M14 family. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by thrombin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin / thrombomodulin complex. CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. CPB2 exhibits carboxypeptidase activity and activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
Carboxypeptidase B2 / CPB2抗体相关产品如下：
hz-12857R phospho-beta Catenin (Tyr489)磷酸化β-连环蛋白/β-连环素/β链接素抗体
hz-12858R phospho-beta Catenin (Tyr86)磷酸化β-连环蛋白/β-连环素/β链接素抗体
hz-12859R beta Crystallin A3βA3/A1-crystallin蛋白抗体
hz-12860R Beta crystallin SγS-crystallin蛋白抗体
hz-15078R C1orf851号染色体开放阅读框85抗体
hz-15080R C1orf871号染色体开放阅读框87抗体
hz-15081R C1ORF951号染色体开放阅读框95抗体
hz-15088R C1s 补体C1S链多肽抗体
hz-15089R C20orf10620号染色体开放阅读框106抗体
hz-15090R C20orf10720号染色体开放阅读框107抗体
hz-15091R C20orf11720号染色体开放阅读框117抗体
hz-15092R C20orf11820号染色体开放阅读框118抗体
hz-15095R C20ORF14420号染色体开放阅读框144抗体
hz-15096R C20orf15120号染色体开放阅读框151抗体
hz-15117R c20orf7820号染色体开放阅读框78抗体
hz-15103R C20orf18720号染色体开放阅读框187抗体
hz-15126R C21orf5921号染色体开放阅读框59抗体
hz-15097R C20orf152 20号染色体开放阅读框152抗体
hz-15098R C20orf16520号染色体开放阅读框165抗体
hz-15099R C20orf16620号染色体开放阅读框166抗体
hz-15100R C20orf17320号染色体开放阅读框173抗体
hz-15106R C20orf2420号染色体开放阅读框24抗体
hz-15109R C20orf30 20号染色体开放阅读框30抗体
hz-15111R C20orf420号染色体开放阅读框4抗体
hz-15113R C20orf720号染色体开放阅读框7抗体
hz-15118R C20orf79 20号染色体开放阅读框79抗体
hz-15119R C20orf9420号染色体开放阅读框94抗体
hz-15125R C21orf3721号染色体开放阅读框37抗体
hz-15132R C22orf15 22号染色体开放阅读框15抗体
hz-15131R C22orf1322号染色体开放阅读框13抗体
hz-15134R C22orf2622号染色体开放阅读框26抗体
hz-15142R C2b补体C2b链多肽抗体
hz-15147R C2orf162号染色体开放阅读框16抗体
hz-15148R C2orf27 2号染色体开放阅读框27抗体
hz-12989R phospho-delta 1 Catenin (Ser268)磷酸化δ连环蛋白抗体
hz-12990R phospho-delta 1 Catenin (Thr310)磷酸化δ连环蛋白抗体
hz-12991R phospho-delta 1 Catenin (Thr916)磷酸化δ连环蛋白抗体
hz-12992R phospho-delta 1 Catenin (Tyr228)磷酸化δ连环蛋白抗体
hz-12993R phospho-delta 1 Catenin (Tyr291)磷酸化δ连环蛋白抗体
hz-12994R phospho-delta 1 Catenin (Tyr96)磷酸化δ连环蛋白抗体
hz-15140R C22orf43 22号染色体开放阅读框43抗体
hz-15143R C2CD3C2CD3蛋白抗体
hz-10136R Caspase 14半胱胺酸蛋白酶蛋白14抗体
hz-15178R C3orf553号染色体开放阅读框55抗体