CD36 / SCARB3抗体

CD36 / SCARB3抗体产品信息

免疫原 :
Recombinant Human CD36 / SCARB3 protein (Catalog#10752-H08H)
Reagents : FITC-conjugated rabbit monoclonal antibody
Clone ID :
001
抗体宿主 :
Rabbit IgG
Concentration :
10 μl/Test, 0.1 mg/ml
缓冲液 : Aqueous solution containing 0.5% BSA and 0.09% sodium azide
制备方法 :
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD36 / SCARB3 (rh CD36 / SCARB3; Catalog#10752-H08H; NP_001001547.1; Gly 30-Asn 439) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
CD36 / SCARB3抗体 Background
Platelet glycoprotein 4, also known as Leukocyte differentiation antigen CD36, GPIIIB, GP3B, FAT, and CD36, is integral membrane proteinfound on the surface of many cell types in vertebrate animals. It belongs to theCD36 family and is found on platelets, erythrocytes, monocytes, differentiated adipocytes, mammary epithelial cells, spleen cells and some skin microdermal endothelial cells. CD36 has also been implicated in hemostasis, thrombosis, malaria, inflammation, lipid metabolism andatherogenesis. CD36 seems to have numerous potential physiological functions. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and binds long chain fatty acids. CD36 may also function as a cell adhesion molecule and in the transport and/or as a regulator of fatty acid transport. Defects in CD36 are the cause of platelet glycoprotein IV deficiencyalso known as CD36 deficiency. As a receptor for thrombospondin 1, CD36 plays a role in the regulation of angiogenesis, which may be a therapeutic strategy for controlling the dissemination of malignant neoplasms.
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