IL-28B / IFN-lambda-3抗体

IL-28B / IFN-lambda-3抗体产品信息免疫原 : Recombinant Human IL-28B / IFN-lambda-3 protein (Catalog#11890-H08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Human IL-28B / IFN-lambda-3 (rh IL-28B / IFN-lambda-3; Catalog#11890-H08H; NP_742151.2; Met 1-Val 196). IL-28B / IFN-lambda-3 specific IgG was purified by Human IL-28B / IFN-lambda-3 affinity chromatography.
IL-28B / IFN-lambda-3抗体 Background
Interleukin-28B, also known as IL-28B, Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, Interleukin-28C, IL28B and IFNL3, is a secreted protein which belongs to theIL-28/IL-29 family. Interleukin-28B / IL28B is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. Interleukin-28B / IL28B displays potent antiviral activity. It also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. IL28B contributes to viral resistance and is known to be upregulated by interferons and by RNA virus infection. Hepatitis C Virus (HCV) infection is spontaneously resolved in about 30% of acutely infected individuals. In those who progress to chronic hepatitis C, HCV therapy permanently eradicates infection in about 40% of cases. It has long been suspected that host genetic factors are key determinants for the control of HCV infection. Genetic variation in Interleukin-28B / IL28B is the strongest predictor for the control of HCV infection. Importantly, single nucleotide polymorphisms (SNPs) in IL28B strongly predicted both spontaneous and treatment-induced HCV recovery.
IL-28B / IFN-lambda-3抗体相关产品如下：xy-1185xy TRAF3/CD40bp (CD40 binding protein)肿瘤坏死因子受体相关蛋白3抗原
xy-1184xy TRAF6 (TNF receptor-associated factor 6)肿瘤坏死因子受体相关因子6抗原
xy-1214xy TRAIL/Apo2L (tumor necrosis factor-related apoptosis-inducing ligand)肿瘤坏死因子相关凋亡诱导配体/凋亡素2配体抗原
xy-1151xy TRBF1 (Telomeric repeat binding factor 1)端粒体复制结合因子1抗原
xy-0964xy TRIM32(tripartite motif protein 32)TRIM32抗原
xy-1243xy Trop-2/Tpm2 peptide原肌球蛋白抗原
xy-1220xy TSARG4(Testis and spermatogenesis related gene 4)生精细胞凋亡相关基因4抗原
xy-0716xy CIDEB peptideCIDEB抗原
xy-1365xy Tsg101(Tumor susceptibility gene 101 protein)Tsg101抗原
xy-2087xy TSHR (Thyroid stimulating hormone receptor)促甲状腺素受体抗原
xy-1534xy MAP1LC3A(microtubule-associated protein 1 light chain 3)自噬微管相关蛋白轻链3抗原
xy-1147xy TSLC1 (tumor suppressor in lung cancer-1)肺癌肿瘤阻抑基因1抗原
xy-0826xy TTF-1 (Thyroid Transcription Factor-1)甲状腺核转录因子-1抗原
xy-1322xy Tubulin- Gamma微管蛋白-γ抗原
xy-2441xy TWIST protein peptideTWIST蛋白抗原
xy-1088xy T Beta10 peptide胸腺素β10抗原
xy-1929xy UCN(Urocortin)mouse ret新型血管活性因子UCN抗原(小鼠、大鼠)
xy-1403xy USF-1(upstream stimulatory factor 1)上游刺激因子1抗原
xy-1549xy Ubiquitin泛素蛋白
xy-1505xy VASH1(Vasohibin 1)兔抗血管抑制蛋白1抗原
xy-0396xy VCAM-1/CD106(Vascular cell adhesion molecule 1 isoform b precusor; CD106 antigen)血管内皮细胞粘附分子抗原
xy-0920xy VCAM-1/CD106 (Vascuolar cell adhesion molecule 1)血管内皮细胞粘附分子抗原
xy-1461xy VDAC peptide电压依赖性阴离子通道抗原
xy-1313xy VEGF血管内皮生长因子(多肽抗原)
xy-1957xy VEGF-A(Vascuoar endothelial growth factor A)血管内皮生长因子A抗原
xy-1586xy VEGF-C(Vascuoar endothelial growth factor-C)血管内皮生长因子C型抗原
xy-0565xy VEGFR2血管内皮生长因子受体2
xy-2089xy sVEGFR2可溶性血管内皮生长因子受体2
xy-1083xy VEGFR-3/FLt-4血管内皮细胞生长因子受体-3（多肽）
xy-2202xy VEGFR-3(Vascular Epidemal growth factor receptor-3)血管内皮细胞生长因子受体-3抗原
xy-0586xy VWF (Von Willebrand Factor)血管假性血友病因子/血管性血友病因子抗原
xy-1739xy Wnt1信号通路Wnt1抗原
xy-0589xy WWOX (WW domain-containing oxidoreductase)包含氧化还原酶的WW域抗原