IL10RB / IL10R2抗体

IL10RB / IL10R2抗体产品信息免疫原 : Recombinant Mouse IL10RB / IL10R2 protein (Catalog#50846-M08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Mouse IL10RB / IL10R2 (rM IL10RB / IL10R2; Catalog#50846-M08H; NP_032375.2; Met 1-Ser 222). IL10RB / IL10R2 specific IgG was purified by Mouse IL10RB / IL10R2 affinity chromatography.
IL10RB / IL10R2抗体 Background
The functional IL-10 receptor consists of two polypeptide chains, a ligand binding chain IL-10 Rα (IL-10 R1) and a signal transduction molecule known as IL-10 Rβ (IL-10 R2). Both chains of the IL-10 R are expressed on many hematopoietic cells, including lymphocytes, monocytes and neutrophils, with the IL-10 Rβ chain expressed at higher levels than the IL-10 Rα chain in most cases. Interleukin 10 receptor beta (IL-10 Rβ), also known as CD210b and CRF2-4, is an 80-85 kDa member of the type II cytokine receptor family of proteins and contains two fibronectin type-III domains. The widely expressed IL-10 Rβ serves as a signal transducing accessory chain not only for IL-10, but also for other interleukins including IL-22, -28A, -28B and -29 (plus IL-26 in human) when complexed to the ligand-binding chains. It has been shown that the action of IL-10 delivered through its receptor can affect a variety of immune functions including inhibition of pro-inflammatory cytokine synthesis and regulation of the growth and function of B cells and antigen presenting cells. The human IL-10 Rβ shares 69% homology to its mouse counterpart in amino acid sequence. Research evidences indicated that defects in IL10RB are associated with susceptibility to hepatitis B virus infection.
IL10RB / IL10R2抗体相关产品如下：xy-0345M-xyE-xyY5 Mouse Anti-human IgM/PE-CY5PE-CY5标记的小鼠抗人IgM
xy-0345M-Axyxy Mouse Anti-human IgM/APCAPC标记的小鼠抗人IgM
xy-0345M-AF350 Mouse Anti-human IgM/Alexa Fluor 350Alexa Fluor 350标记的小鼠抗人IgM
xy-0345M-AF488 Mouse Anti-human IgM/Alexa Fluor 488Alexa Fluor 488标记的小鼠抗人IgM
xy-0345M-AF555 Mouse Anti-human IgM/Alexa Fluor 555Alexa Fluor 555标记的小鼠抗人IgM
xy-0345M-AF647 Mouse Anti-human IgM/Alexa Fluor 647Alexa Fluor 647标记的小鼠抗人IgM
xy-0345M-xyE-xyy5.5 Mouse Anti-human IgM/PE-Cy5.5PE-Cy5.5标记的小鼠抗人IgM
xy-0345M-xyE-xyy7 Mouse Anti-human IgM/PE-Cy7PE-Cy7标记的小鼠抗人IgM
xy-0345M-Axy Mouse Anti-human IgM/AP碱性磷酸酶（AP）标记的小鼠抗人IgM
xy-0345M-Golxy Mouse Anti-human IgM/Gold胶体金标记的小鼠抗人IgM
xy-0345M-xyy7 Mouse Anti-human IgM/Cy7Cy7标记的小鼠抗人IgM
xy-0345M-xyE Mouse Anti-human IgM/PEPE标记的小鼠抗人IgM
xy-0294M-RBITxy Mouse Anti-Goat IgG/RBITC罗丹明标记的小鼠抗羊IgG
xy-0294M-Golxy Mouse Anti-Goat IgG/Gold胶体金标记的小鼠抗羊IgG
xy-0294M-Axy Mouse Anti-Goat IgG/AP碱性磷酸酶（AP）标记的小鼠抗羊IgG
xy-0294M-Bio Mouse Anti-Goat IgG/Bio生物素标记的小鼠抗羊IgG
xy-0294M-AF647 Mouse Anti-Goat IgG/Alexa Fluor 647Alexa Fluor 647标记的小鼠抗羊IgG
xy-0294M-xyE-xyy5.5 Mouse Anti-Goat IgG/PE-Cy5.5PE-Cy5.5标记的小鼠抗羊IgG
xy-0294M-xyE-xyy7 Mouse Anti-Goat IgG/PE-Cy7PE-Cy7标记的小鼠抗羊IgG
xy-0294M-AF488 Mouse Anti-Goat IgG/Alexa Fluor 488Alexa Fluor 488标记的小鼠抗羊IgG
xy-0294M-xyy3 Mouse Anti-Goat IgG/Cy3Cy3标记的小鼠抗羊IgG
xy-0294M-xyy5 Mouse Anti-Goat IgG/Cy5Cy5标记的小鼠抗羊IgG
xy-0294M-xyy5.5 Mouse Anti-Goat IgG/Cy5.5Cy5.5标记的小鼠抗羊IgG
xy-0294M-xyy7 Mouse Anti-Goat IgG/Cy7Cy7标记的小鼠抗羊IgG
xy-0294M-xyE Mouse Anti-Goat IgG/PEPE标记的小鼠抗羊IgG
xy-0294M-xyE-xyy3 Mouse Anti-Goat IgG/PE-Cy3PE-Cy3标记的小鼠抗羊IgG
xy-0294M-xyE-xyY5 Mouse Anti-Goat IgG/PE-CY5PE-CY5标记的小鼠抗羊IgG
xy-0294M-Axyxy Mouse Anti-Goat IgG/APCAPC标记的小鼠抗羊IgG
xy-0295M-Bio Mouse Anti-rabbit IgG/Bio生物素标记的小鼠抗兔IgG
xy-0295M-HRxy Mouse Anti-rabbit IgG/HRP辣根过氧化物酶标记的小鼠抗兔IgG
xy-0295M-xyy7 Mouse Anti-rabbit IgG/Cy7Cy7标记的小鼠抗兔IgG
xy-0295M-xyE Mouse Anti-rabbit IgG/PEPE标记的小鼠抗兔IgG
xy-0295M-xyE-xyy3 Mouse Anti-rabbit IgG/PE-Cy3PE-Cy3标记的小鼠抗兔IgG
xy-0295M-Axyxy Mouse Anti-rabbit IgG/APCAPC标记的小鼠抗兔IgG
xy-0295M-xyy5 Mouse Anti-rabbit IgG/Cy5Cy5标记的小鼠抗兔IgG