IL10RB / IL10R2抗体

IL10RB / IL10R2抗体产品信息

免疫原 :
Recombinant Mouse IL10RB / IL10R2 protein (Catalog#50846-M08H)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Mouse IL10RB / IL10R2 (rM IL10RB / IL10R2; Catalog#50846-M08H; NP_032375.2; Met 1-Ser 222). IL10RB / IL10R2 specific IgG was purified by Mouse IL10RB / IL10R2 affinity chromatography.
IL10RB / IL10R2抗体 Background
The functional IL-10 receptor consists of two polypeptide chains, a ligand binding chain IL-10 Rα (IL-10 R1) and a signal transduction molecule known as IL-10 Rβ (IL-10 R2). Both chains of the IL-10 R are expressed on many hematopoietic cells, including lymphocytes, monocytes and neutrophils, with the IL-10 Rβ chain expressed at higher levels than the IL-10 Rα chain in most cases. Interleukin 10 receptor beta (IL-10 Rβ), also known as CD210b and CRF2-4, is an 80-85 kDa member of the type II cytokine receptor family of proteins and contains two fibronectin type-III domains. The widely expressed IL-10 Rβ serves as a signal transducing accessory chain not only for IL-10, but also for other interleukins including IL-22, -28A, -28B and -29 (plus IL-26 in human) when complexed to the ligand-binding chains. It has been shown that the action of IL-10 delivered through its receptor can affect a variety of immune functions including inhibition of pro-inflammatory cytokine synthesis and regulation of the growth and function of B cells and antigen presenting cells. The human IL-10 Rβ shares 69% homology to its mouse counterpart in amino acid sequence. Research evidences indicated that defects in IL10RB are associated with susceptibility to hepatitis B virus infection.
IL10RB / IL10R2抗体相关产品如下：
hz-2811R HDAC6组蛋白去乙酰化酶6抗体
hz-3215R phospho-HDAC6 (Ser22)磷酸化组蛋白去乙酰化酶6抗体
hz-2890R HDAC7组蛋白去乙酰化酶7抗体
hz-3216R phospho-HDAC7 (Ser358)磷酸化组蛋白去乙酰化酶7抗体
hz-2891R HDAC8组蛋白去乙酰化酶8抗体
hz-3184R Phospho-HER4 (Tyr984)磷酸化HER4抗体
hz-6458R HARS组氨酸tRNA连接酶抗体
hz-4529R NDV HN protein鸡新城疫血凝素－神经氨酸酶抗体
hz-1387R HSP105热休克蛋白105抗体
hz-1405R HNF1肝细胞核因子1α抗体
hz-1407R HIF-1 beta缺氧诱导因子1β /HIF-1β抗体
hz-1409R HSTF2热休克转录因子2抗体
hz-0966R HA tagHA tag标签抗体
hz-9066R HIG1缺氧诱导基因1蛋白抗体
hzm-2026M HCG alpha(4A8)人绒毛膜促性腺激素α 亚基单抗
hzm-2024M HBsAg(H2F4)人乙型肝炎表面抗原单克隆抗体（检测）
hzm-2022M HBeAg (2E9)人乙型肝炎e抗原单克隆（包被）抗体
hzm-2023M HBeAg(2E6)人乙型肝炎e抗原单克隆（检测）抗体
hzm-2118M hHb(H5A3)小鼠抗人血红蛋白单克隆抗体
hz-2001R H1N1 Hemagglutinin 1甲型流感病毒血凝素抗体
hz-3213R Phospho-HER2(Tyr1112)磷酸化HER2受体抗体
hz-2809R HDAC4组蛋白去乙酰化酶4抗体
hz-3212R Phospho-HER2 (Tyr1221 + Tyr1222)磷酸化HER2受体抗体
hz-3127R phospho-HDAC8 (Ser39)磷酸化组蛋白去乙酰化酶8抗体
hz-1198R HLA-DRHLA-DR抗体
hz-0752R HLA G人类白细胞抗原G抗体
hz-0556R HMGA2高迁移率族蛋白A2抗体
hz-0664R HMGB1高迁移率族蛋白B1抗体
hz-1238R HO-2血红素氧合酶2抗体
hz-0394R HOXc8HOXc8抗体
hz-1071R HRAS原癌基因H-ras抗体
hz-0191R HSP60热休克蛋白-60抗体
hz-0126R HSP70热休克蛋白-70抗体
hz-0696R HSP90 alpha热休克蛋白90α抗体
hz-0135R HSP90 beta热休克蛋白90β/HSP90 β 抗体
hz-0896R HCMV UL23人巨细胞病毒UL23抗体
hz-9702R HECAHECA蛋白抗体
hz-9091R hnRNP A2B1异质核糖核蛋白hnRNPA2抗体
hz-9092R hnRNP U异质核糖核蛋白U抗体
hz-1719R HPV16 E6 + HPV18 E6人类乳头状瘤病毒16/18 E6抗体
hz-0843R HA tagHA tag标签抗体
hz-0455R HSL/LIPE荷尔蒙敏感脂肪酶抗体
hz-0847R HBA1血红蛋白α1/α-Globin抗体
hz-6353R HIPK2Fas相互作用蛋白激酶2抗体
hz-6777R HIPK3Fas相互作用蛋白激酶3抗体
hz-0860R HHV8 ORF50人类疱疹病毒8抗体
hz-3180R Phospho-HSP27 (Ser82)磷酸化热休克蛋白27抗体
hz-0870R HHV8/ORF K2人类疱疹病毒8抗体
hz-0859R HHV8 ORF50人类疱疹病毒8抗体