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- 详细信息
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within human Mimitin.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H
- 宿主:
Rabbit
- 应用范围:
E, WB, IF
- 浓度:
见详细说明信息
- 靶点:
Mimitin
- 抗体英文名:
Mimitin Antibody
- 抗体名:
Mimitin Antibody
- 规格:
0.1 mg
Mimitin Antibody产品详细介绍:
| 产品名称: | Mimitin Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 254159 |
| 规格: | 0.1 mg |
| 产品描述: | Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kappaB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within human Mimitin. |
| 适用物种: | H |
| 应用范围: | E, WB, IF |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IF: 1:100-1:500 |
| 别名: | Mimitin; NADH dehydroxygenase (ubiquinone) 1 alpha subcomplex; assembly factor 2; NDUFAF2; NDUFA12L; MMTN |
| 形态: | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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Mimitin Antibody
¥3000 - 3999










