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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NOS1.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆抗体
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
NOS-1
- 抗体英文名:
NOS-1 Antibody
- 抗体名:
NOS-1 Antibody
- 规格:
0.1 mg
NOS-1 Antibody产品详细介绍:
| 产品名称: | NOS-1 Antibody |
| 说明书: | http://www.abbiotec.com/antibodies/nos-1-antibody【参考图片】 |
| 货号: | 250783 |
| 规格: | 0.1 mg |
| 产品描述: | Nitric oxide synthases (NOS) are enzymes that catalyze the generation of nitric oxide (NO) from L-arginine and require nicotinamide adenine dinucleotide phosphate (NADPH) as a cofactor. At least three NOS isoforms have been identified: neuronal NOS (nNOS or NOS1 or bNOS), inducible NOS (iNOS or NOSII) and endothelial NOS (eNOS or NOS III). NOS-1 produces NO which is a messenger molecule with diverse functions throughout the body. NO behaves as a neurotransmitter in the brain and peripheral nervous system. Genetic variations of NOS1 gene are associated with susceptibility to infantile pyloric stenosis type 1 (IHPS1). |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NOS1. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500 |
| 别名: | Nitric oxide synthase, brain; bNOS; NOS type I; Neuronal NOS; N-NOS; nNOS; Constitutive NOS; NC-NOS; NOS1; NOS-1 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Immunohistochemical Localization of NOS Isoforms
Three distinct isoforms of nitric oxide synthases (NOS) have so far been identified and cloned (1 ). There are two constitutively expressed NOS—neuronal (n) and endothelial (e), NOS—and one inducible (i) form, iNOS
Detection of NOS Isoforms by Western-Blot Analysis
The amount of nitric oxide synthase (NOS) in tissues and cells can readily be determined by Western blotting. Antibodies are now commercially available for the detection of the inducible (i), neuronal (n), and endothelial (e) NOS
A Microtiter-Plate Assay of Human NOS Isoforms
Nitric oxide synthase (NOS) catalyzes the conversion of L -arginine, molecular oxygen, and nicotinamide adenine dinucleotide phosphate (NADPH) to NO, citrulline, and NADP+ (reviewed in ref. 1 ). The neuronal (n) and endothelial (e) NOS
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