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- 文献和实验
- 技术资料
- 英文名:
Recombinant Human S100 Calcium Binding Protein A4
- 供应商:
艾美捷科技有限公司
- 规格:
2μg&5μg&10μg
【产品形式】:艾美捷为您提供的【S100A4】重组人S100钙结合蛋白A4蛋白产品是Sterile Filtered clear solution. S100A4 at 0.1mg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol.
【背景资料】:S100A4 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 may function in motility, invasion, and tubulin polymerization. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21. Chromosomal rearrangements and altered expression of the S100A4 gene have been implicated in tumor metastasis.
以色列ProSpec-Tany公司专注于细菌来源重组蛋白质生产。其独有细菌和哺乳动物表达和蛋白折叠技术使其成为国际一流科研级蛋白供应商。ProSpec-Tany是世界上能提供蛋白种类最多公司之一。领先生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。作为多家知名品牌代理,艾美捷与ProSpec一起为研究者们提供最好、最新细胞生物学研究工具而不断扩大产品及服务质量。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看中国生命科学试剂产品评论网站。
点击【S100A4】重组人S100钙结合蛋白A4查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-1454垂询Prospec中国区域授权总代理艾美捷科技有限公司。
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文献和实验Characterization of Epithelial Cells in the Hair Follicle With S100 Proteins
S100 proteins are the largest subgroup of Ca2+ binding proteins with the EF-hand structural motif. A unique feature of this protein family is that individual members are localized in specific cellular compartments. For example, various S100
Characterization of Calcium Channel Binding
calcium channels are expressed in a variety of tissues including heart, muscles and brain. Saturation binding of a radioligand to the calcium channel is commonly used to characterize the expression level of the channel protein. Compound competition binding
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calcium binding protein A8 (S100A8) ELISA kit; CSB-EL020641MOMouse Protein S100-A9(S100A9) ELISA kit; CSB-EL020642MO 研究亮点 研究发现SFTSV可感染雄性小鼠生殖道(睾丸、附睾等),靶向间质细胞诱导凋亡和焦亡,降低睾酮水平并损害精子发生。单细胞测序揭示CCR2⁺/SPP1⁺巨噬细胞浸润驱动附睾炎症和纤维化,S100A4抑制剂氯硝柳胺可减轻病理损伤并降低死亡率。动物实验提示潜在性传播风险
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