【ER-a】重组人雌激素受体α | Recombinant

【产品形式】：艾美捷为您提供的【ER-a】重组人雌激素受体α蛋白产品是Sterile Filtered clear solution. ER ? in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.

【背景资料】：Estrogen receptor is a ligand-activated transcription factor composed of several domains essential for hormone binding, DNA binding, and activation of transcription. Estrogen and its receptors are crucial for sexual development and reproductive function, but also play a role in other tissues such as bone. The Estrogen Receptor is a significant regulator of growth and differentiation in the mammary gland. Estrogen receptors are also implicated in pathological processes including breast cancer, endometrial cancer, and osteoporosis. The presence of estrogen receptors in breast tumors indicates an increased probability of response to anti-estrogen therapy (e.g. tamoxifen). The Estrogen Receptor gene is divided into 8 exons having a genomic length of more than 140kbp.The Estrogen Receptor has 6 functionally separate domains, named A - F. Alternative splicing results in a number of transcript variations, which differ in their 5’ UTRs and use different promoters. The protein is restricted to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2.

以色列ProSpec-Tany公司专注于细菌来源重组蛋白质生产。其独有细菌和哺乳动物表达和蛋白折叠技术使其成为国际一流科研级蛋白供应商。ProSpec-Tany是世界上能提供蛋白种类最多公司之一。领先生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。作为多家知名品牌代理，艾美捷与ProSpec一起为研究者们提供最好、最新细胞生物学研究工具而不断扩大产品及服务质量。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看中国生命科学试剂产品评论网站。

点击【ER-a】重组人雌激素受体α查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-1454垂询Prospec中国区域授权总代理艾美捷科技有限公司。