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- 2025年07月07日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Human Calpain-1 Catalytic Subunit
- 供应商：
艾美捷科技有限公司
- 规格：
2μg&5μg&10μg
【产品形式】：艾美捷为您提供的【CAPN1】人钙蛋白酶-1催化亚基蛋白产品是Sterile Filtered colorless solution. 50mM imidazole-HCl, 100mM NaCl, 5mM EGTA, 1mM DTT and 10% sucrose.
【背景资料】：Calpain’s activity is attributed to two main isoforms: ?-calpain and m-calpain, which are ubiquitously, expressed proteases implicated in cellular migration, cell cycle progression, degenerative processes and cell death. These heterodimeric enzymes are composed of distinct catalytic subunits, encoded by Capn1 (?-calpain) or Capn2 (m-calpain), and a common regulatory subunit encoded by Capn4. CAPN1 is a calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of the substrates involved in cytoskeletal remodeling and signal transduction. CAPN1 is activated by micromolar concentrations of calcium and inhibited by calpastatin.
以色列ProSpec-Tany公司专注于细菌来源重组蛋白质生产。其独有细菌和哺乳动物表达和蛋白折叠技术使其成为国际一流科研级蛋白供应商。ProSpec-Tany是世界上能提供蛋白种类最多公司之一。领先生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。作为多家知名品牌代理，艾美捷与ProSpec一起为研究者们提供最好、最新细胞生物学研究工具而不断扩大产品及服务质量。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看中国生命科学试剂产品评论网站。
点击【CAPN1】人钙蛋白酶-1催化亚基查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-1454垂询Prospec中国区域授权总代理艾美捷科技有限公司。
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文献和实验(3 ). PKA is composed of two catalytic (C) and two regulatory (R) subunits and has type I and type II isozymes, with different R subunits, termed RI and RII, interacting with an identical C subunit (1 ). Thus far, four isoforms of R subunits, RIα, RIβ, RIIα
The Immortalization of Human Endometrial Cells
enzyme that prevents loss of telomeric DNA associated with normal cell division. Transfection of cells with vectors expressing the catalytic subunit of human telomerase (hTERT) is often sufficient for immortalization. In this article, we will address
Assay of mtDNA Polymerase from Human Tissues
associated with at least four other unidentified cellular proteins ( 4 ). Both α- and β-subunits have been cloned ( 5 – 7 ). The α-subunit is catalytic and contains both the polymerase and the 3′ to 5′ proofreading exonuclease
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