钠钙交换蛋白又称钠钙交换体,有三种同分异构体,即NCX1、NCX2和NCX3。3型Na-Ca交换蛋白-NCX3, 主要在脑组织表达,分布与胞浆及胞膜。
SLC8A3 is a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner.
Also known as: Na+/Ca2+ exchanger3; Na+/Ca2+ exchange protein 3; Na+/Ca2+ exchanger 3; NCX3; SCL8A3; Sodium calcium exchanger form 3; Sodium/calcium exchanger SLC8A3; Solute carrier family 8 sodium calcium exchanger member 3