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Renin Fluorogenic Substrate

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  • Cayman已认证
  • USA
  • 10006906
  • 2025年07月13日
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    • 详细信息
    • 文献和实验
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    • 供应商

      Neobioscience

    • 保存条件

      -20

    • 规格

      1 mg

    Renin is an aspartyl protease of approximately 40 kDa that converts angiotensinogen into angiotensin I.{12331} The renin fluorogenic substrate consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other.{12969} After cleavage by renin, the product (peptide-EDANS) is brightly fluorescent and can be easily analyzed using an excitation wavelength of 340 nm and emission wavelengths of 485-510 nm.

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    相关实验
    • Triglyceride Lipase Assays Based on a Novel Fluorogenic Alkyldiacyl Glycerol Substrate

      Lipases are responsible for extracellular degradation and intracellular metabolism of lipids in animals, plants, and microorganisms. The conformational motif of all lipases whose three-dimensional structure has been determined

    • Measurement of Plasma Renin Activity

      Measurement of angiotensin 1, released in plasma by the action of endogenous enzyme renin on endogenous substrate, angiotensinogen is described. Details are given for the generation of angiotensin 1 from plasma using controlled conditions

    • In Vitro Studies on Renin Release

      of angiotensin I (ANG I) from renin substrate; angiotensin I is further converted to the physiologically active form angiotensin II by angiotensin-converting enzyme (ACE). Angiotensin II (ANG II) is an important vasoconstrictor, and it promotes release

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