• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        In Vitro Studies on Renin Release

        互联网

        276
        Renin is an aspartyl peptidase that is synthesized, stored, and released from juxtaglomerular (JG) granular cells in the lamina media of the afferent arteriole. Each afferent arteriole contains 5–20 JG cells. Renin catalyzes the cleavage of angiotensin I (ANG I) from renin substrate; angiotensin I is further converted to the physiologically active form angiotensin II by angiotensin-converting enzyme (ACE). Angiotensin II (ANG II) is an important vasoconstrictor, and it promotes release of aldosterone from the adrenal gland. Thus, the renin-angiotensin-aldosterone system is important in the regulation of salt and water homeostasis and blood pressure. In keeping with its complex homeostatic roles, the regulation of renin secretion is under the control of a number of systemic factors. Release is stimulated by decreases in arterial pressure, increases in sympathetic nervous activity, and by a decrease in the tubular NaCl concentration at the macula densa (MD).
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序