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- 文献和实验
- 技术资料
- 抗体名:
HER3 Antibody (PE) 抗体
- 抗体英文名:
HER3 Antibody (PE)
- 靶点:
HER3
- 应用范围:
FC
- 适应物种:
Human
- 保质期:
12 months from date of receipt.
- 抗原来源:
详询
- 目录编号:
orb3012943
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
PE
- 克隆性:
Monoclonal
- 保存条件:
详询
- 亚型:
Mouse IgG2a kappa
- 免疫原:
详询
- 规格:
100 T
描述: HER3 Antibody (PE)
克隆号: H3Mab-17
别名: ERBB3, FERLK, LCCS2
应用说明: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
免疫原: HER3-transfected CHO cells
防腐剂: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
纯化方法: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
特异性: The mouse monoclonal antibody H3Mab-17 recognizes an extracellular epitope on human HER3 (erbB3), a member of EGFR family of receptor tyrosine kinases, which is overexpressed in many cancers.
研究领域: Signal Transduction
UniProt ID: P21860
Entrez 基因 ID: 2065
保存条件: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
备注: For research use only.

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文献和实验Western Blotting with Horseradish Pe
7.5, 100mM NaCl, 0.1% Tween 20). 2.Incubate the blot for 30 minutes at 37℃, 1 hour at room temperature, or overnight at 4℃. INCUBATION WITH HORSERADISH PEROXIDASE CONJUGATED ANTIBODY NOTE: THE INCLUSION OF SODIUM AZIDE IS TO BE AVOIDED IN ALL STEPS
ERBB3/HER3最-新靶点进展:从“不可成药”到ADC与双抗ADC的分层格局
ERBB3/HER3因其激酶结构域缺陷,长期被视为难以成药的“伪靶点”,其致癌功能高度依赖与HER2/EGFR的异二聚化。2026年的临床证据表明,靶向策略的重心已从信号阻断型单抗,彻底转向不依赖激酶活性、通过内吞递送细胞毒载荷的ADC,以及同时阻断二聚化与递送载荷的双特异性ADC。SHR-A2009的首--个III期研究达到主要终点并获上市申请受理,标志着HER3 ADC向监管批准迈出了实质性一步。与此同时,iza-bren(BL-B01D1)作为EGFR×HER3双抗ADC,在乳腺
T-cell dependent antigen specific in situ staining (Pe)
if you have them). Let them dry approx 1 hour in a dry atmosphere at RT. Antibodies (anti-Pe) in the sections degrade more rapidly than tissue antigens. Proceed with staining within 24 hours or freeze the slides. Antigen-specific staining: (Pe staining of Pe
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