HER3 Antibody (PE) 抗体,orb3012943,Biorbyt产品图

HER3 Antibody (PE) 抗体,orb30129

43,Biorbyt
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  • ¥7020
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  • orb3012943
  • 英国
  • 2026年08月07日
  • FC
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名:

      HER3 Antibody (PE) 抗体

    • 抗体英文名:

      HER3 Antibody (PE)

    • 靶点:

      HER3

    • 应用范围:

      FC

    • 适应物种:

      Human

    • 保质期:

      12 months from date of receipt.

    • 抗原来源:

      详询

    • 目录编号:

      orb3012943

    • 级别:

      科研

    • 库存:

      99

    • 供应商:

      Biorbyt

    • 标记物:

      PE

    • 克隆性:

      Monoclonal

    • 保存条件:

      详询

    • 亚型:

      Mouse IgG2a kappa

    • 免疫原:

      详询

    • 规格:

      100 T

    类别: Antibodies

    描述: HER3 Antibody (PE)

    克隆号: H3Mab-17

    别名: ERBB3, FERLK, LCCS2

    应用说明: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    免疫原: HER3-transfected CHO cells

    防腐剂: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    纯化方法: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    特异性: The mouse monoclonal antibody H3Mab-17 recognizes an extracellular epitope on human HER3 (erbB3), a member of EGFR family of receptor tyrosine kinases, which is overexpressed in many cancers.

    研究领域: Signal Transduction

    UniProt ID: P21860

    Entrez 基因 ID: 2065

    保存条件: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

    备注: For research use only.

    产品细节图片1
    Separation of MCF-7 cells stained using anti-human HER3 (H3Mab-17) PE antibody (concentration in sample 0.56 µg/ml, red-filled) from MCF-7 cells stained using mouse IgG2a isotype control (MOPC-173) PE antibody (concentration in sample 0.56 µg/ml, same as HER3 PE concentration, black-dashed) in flow cytometry analysis (surface staining).

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    图标文献和实验
    相关实验
    • Western Blotting with Horseradish Pe

      7.5, 100mM NaCl, 0.1% Tween 20). 2.Incubate the blot for 30 minutes at 37℃, 1 hour at room temperature, or overnight at 4℃. INCUBATION WITH HORSERADISH PEROXIDASE CONJUGATED ANTIBODY NOTE: THE INCLUSION OF SODIUM AZIDE IS TO BE AVOIDED IN ALL STEPS

    • ERBB3/HER3最-新靶点进展:从“不可成药”到ADC与双抗ADC的分层格局

      ERBB3/HER3因其激酶结构域缺陷,长期被视为难以成药的“伪靶点”,其致癌功能高度依赖与HER2/EGFR的异二聚化。2026年的临床证据表明,靶向策略的重心已从信号阻断型单抗,彻底转向不依赖激酶活性、通过内吞递送细胞毒载荷的ADC,以及同时阻断二聚化与递送载荷的双特异性ADC。SHR-A2009的首--个III期研究达到主要终点并获上市申请受理,标志着HER3 ADC向监管批准迈出了实质性一步。与此同时,iza-bren(BL-B01D1)作为EGFR×HER3双抗ADC,在乳腺

    • T-cell dependent antigen specific in situ staining (Pe)

      if you have them). Let them dry approx 1 hour in a dry atmosphere at RT. Antibodies (anti-Pe) in the sections degrade more rapidly than tissue antigens. Proceed with staining within 24 hours or freeze the slides. Antigen-specific staining: (Pe staining of Pe

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