重组人雌激素受体结合位点关联抗原9(EBAG9)

产品英文名称：
Recombinant Human Estrogen Receptor Binding Site Associated Antigen 9

英文简称:
EBAG9

中文名称:
重组人雌激素受体结合位点关联抗原9

背景资料:
EBAG9 is a type III transmembrane protein that is primarily located in the Golgi. EBAG9 is a tumor-associated antigen that is expressed at high frequency in a variety of cancers， such as advanced breast and prostate cancers. while the EBAG9 acts to inhibit the growth of receptor-binding cells and induced apoptosis of immune cells， cancer cells may evade immune surveillance. Thus immunodetection of EBAG9 expression can be a negative prognostic indicator. EBAG9 promotes progression of bladder cancer. In rheumatoid arthritis， the deficiency of EBAG9 induces CTL infiltration through failure to evade immune attack， therefore leading to apoptosis of the synovial lining cells. EBAG9 is involved in controlling exocytosis processes. EBAG9 expression plays a role in the progression of oral squamous cell carcinoma. EBAG9 plays a specific role in premature stages of breast carcinogenesis.

产品描述:
EBAG9 Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 207 amino acids （28-213） and having a molecular mass of 23.4 kDa. The EBAG9 protein is fused to 20 amino acid His-Tag at N-terminus and purified by standard chromatography techniques.
来源宿主:
大肠杆菌中重组表达

溶解建议:
Sterile Filtered colorless solution. The EBAG9 protein solution contains 20mM Tris-HCl pH-8， 1mM DTT， 2mM EDTA and 10% glycerol.

保存建议：
EBAG9 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
应用领域：
重组人雌激素受体结合位点关联抗原9产品可广泛应用于内分泌研究、信号传导研究、药物靶点研究、免疫检测研究、抗体开发、功能研究、蛋白互作研究、ELISA检测、Western Blot、免疫组化等生物医学研究领域。

关键词：
重组人雌激素受体结合位点关联抗原9、Recombinant Human Estrogen Receptor Binding Site Associated Antigen 9、EBAG9、重组蛋白、多肽、抗原、激素、受体蛋白

其他简介：

 
CMBIO