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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 保质期:
3 months at -20°C
- 英文名:
B7-H7/HHLA2, His, Cynomolgus
- 库存:
现货
- 供应商:
上海经科化学科技有限公司
- 规格:
100μg/500μg
| 规格: | 100μg | 产品价格: | ¥3000.0 |
|---|---|---|---|
| 规格: | 500μg | 产品价格: | ¥9900.0 |
| Species | Cynomolgus | ||||
| Protein Construction |
|
||||
| Purity | > 95% as determined by Bis-Tris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Loaded B7-H7/HHLA2, His, Cynomolgus on Anti-His-Biosensor can bind Human CD28H, hFc Tag in BLI assay (Gator® Prime). Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 38.31 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
| Target Background | B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. |
| Synonyms | B7H7; B7-H7; HHLA2; B7 Homolog 7 |
产品特点:
1. 【食蟹猴源天然序列】采用食蟹猴 B7-H7(HHLA2)天然氨基酸序列,无突变,与食蟹猴体内天然蛋白结构完全一致,适配食蟹猴来源细胞的实验需求,无种属差异2. 【高活性高特异性】可特异性结合 B7-H7 抗体,ED₅₀ < 100 ng/mL(抗体结合实验),可被 B7-H7 特异性抗体识别,适用于抗体筛选、免疫机制研究3. 【高纯度低内毒素】SDS-PAGE 纯度 > 95%,内毒素 < 0.5 EU/μg(LAL 法),无支原体、细菌、真菌等微生物污染,适配多种科研实验需求4. 【His 标签易纯化检测】哺乳动物细胞表达,C 端带 His 标签,可通过 Ni-NTA 亲和层析快速纯化,也可通过 His 标签抗体进行特异性检测5. 【稳定易保存】蛋白储存液配方优化,未开封 - 80℃可稳定保存 12 个月,-20℃可存 6 个月,避免反复冻融可长期保持蛋白活性6. 【多场景适配】可用于 B7-H7 蛋白结构与功能研究、免疫调控与免疫耐受机制研究、肿瘤免疫治疗研究、非人灵长类疾病模型研究、细胞培养添加剂、药物筛选、抗体研发等
B7-H7,HHLA2, 免疫检查点,食蟹猴源,食蟹猴,重组蛋白,重组,高活性,高纯度,低内毒素,His 标签,细胞培养,免疫细胞,科研实验,哺乳动物细胞表达,Cynomolgus,B7-H7,HHLA2,Recombinant protein,Immune checkpoint,His-tagged,High activity,High purity,Low endotoxin,Cell culture,Immune cell,Mammalian expression
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