- 询价
- BIO-RAD
- MCA722GA
- 2025年10月17日
- C, F
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Human tonsil cells and peripheral blood mononuclear cells.
- 亚型：
IgM
- 形态：
Purified IgM - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
Purified
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
SMØ
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
C, F
- 浓度：
IgM concentration 1 mg/ml
- 抗体名：
CD36 antibody | SMØ
- 规格：
0.1 mg
Mouse anti Human CD36 antibody, clone SMØ recognizes the CD36 antigen, an ~88 kDa cell surface glycoprotein expressed by platelets, monocytes/macrophages and also by some microvascular endothelium and erythroid precursors.
CD36 is the receptor for thrombospondin. When expressed by monocytes and macrophages, CD36 acts as a receptor for oxidized LDL and for apoptotic polymorphonuclear cells. Mouse anti Human CD36 antibody, clone SMØ partially inhibits collagen induced platelet aggregation and macrophage ingestion of apoptotic human neutrophils. It has been reported that this antibody may activate platelets as measured by fibrinogen binding, P-Selectin expression and Annexin V binding - for further details please contact our Technical Services team.
Mouse anti Human CD36 antibody, clone SMØ is also reported to block interaction of oxidized low-density lipoprotein (OXLDL) with CD36 (Sugihara et al.1992).
CD36 is the receptor for thrombospondin. When expressed by monocytes and macrophages, CD36 acts as a receptor for oxidized LDL and for apoptotic polymorphonuclear cells. Mouse anti Human CD36 antibody, clone SMØ partially inhibits collagen induced platelet aggregation and macrophage ingestion of apoptotic human neutrophils. It has been reported that this antibody may activate platelets as measured by fibrinogen binding, P-Selectin expression and Annexin V binding - for further details please contact our Technical Services team.
Mouse anti Human CD36 antibody, clone SMØ is also reported to block interaction of oxidized low-density lipoprotein (OXLDL) with CD36 (Sugihara et al.1992).
储存信息
This product is shipped at ambient temperature.
Store at +4oC.
DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Store at +4oC.
DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | ✓ | 1/10 | 1/20 |
| Immunohistology - Frozen | ✓ | ||
| Immunoprecipitation | × | ||
| Western Blotting | × |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood.
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文献和实验该产品被引用文献
References for CD36 antibody
- Hogg, N. et al. (1984) Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.
Immunology. 53 (4): 753-67. - Pain, A. et al. (2001) Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria.
Proc Natl Acad Sci U S A. 98: 1805-10. - Diaz-Romero, J. et al. (2005) Immunophenotypic analysis of human articular chondrocytes: changes in surface markers associated with cell expansion in monolayer culture.
J Cell Physiol. 202: 731-42. - Biswas, A.K. et al. (2007) Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.
PLoS Pathog. 3: 1271-80. - Sarigianni, M. et al. (2010) Effect of leptin and insulin resistance on properties of human monocytes in lean and obese healthy participants.
Angiology. 61: 768-74.
Further Reading
- Greenwalt, D.E. et al. (1992) Membrane glycoprotein CD36: a review of its roles in adherence, signal transduction, and transfusion medicine.
Blood. 80 (5): 1105-15. - Endemann, G. et al. (1993) CD36 is a receptor for oxidized low density lipoprotein.
J Biol Chem. 268 (16): 11811-6.
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文献支持
Mouse anti Human CD36，clone SMØ
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