GPRC5C Antibody Blocking Peptide(bs-15394P)-500ug

GPRC5C Antibody Blocking Pepti

de(bs-15394P)-500ug
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  • bs-15394P
  • 2025年10月16日
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      500ug

    产品编号bs-15394P
    英文名称GPRC5C Antibody Blocking Peptide
    中文名称G蛋白偶联受体GPRC5C蛋白封闭多肽
    英文别名G-protein coupled receptor family C group 5 member; C; GPC5C; GPRC5C; MGC131820; PSEC0087; RAIG-3; RAIG3; Retinoic acid-induced gene 3 protein; GPC5C_HUMAN.
    纯化方法HPLC
    研究领域

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚细胞定位Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles.
    组织特异性Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG).
    相似性Belongs to the G-protein coupled receptor 3 family.
    功能This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways (By similarity).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPRC5C (G protein-coupled receptor, family C, group 5, member C), also known as RAIG3, is a 441 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and belongs to the G protein-coupled receptor family. Expressed at high levels in stomach, liver, prostate, kidney and pancreas, GPRC5C is thought to function as a retinoic acid-inducible GPR that may play a role in signaling events throughout the cell. GPRC5C is subject to DNA damage-dependent phosphorylation, probably by ATM or ATR.

     

     

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