FREM1 Antibody Blocking Peptide(bs-13213P)-500ug

FREM1 Antibody Blocking Peptid

e(bs-13213P)-500ug
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  • bs-13213P
  • 2025年10月16日
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      500ug

    产品编号bs-13213P
    英文名称FREM1 Antibody Blocking Peptide
    中文名称细胞外基质蛋白FREM1封闭多肽
    英文别名BC037594; BNAR; C9orf143; C9orf145; C9orf154; D430009N09; D630008K06; FLJ25461; FRAS1-related extracellular matrix protein 1; FREM 1; FREM1; FREM1_HUMAN; Heb; MOTA; Protein QBRICK; QBRICK; RGD1306981; RP11-265B7.2; RP23-410K19.1; TILRR.
    纯化方法HPLC
    研究领域

    Developmental Biology > Lineage specification > Ectoderm

    亚细胞定位Secreted; extracellular space; extracellular matrix; basement membrane. Localizes at the basement membrane zone of embryonic epidermis and hair follicles.
    相似性Belongs to the FRAS1 family.
    Contains 1 C-type lectin domain.
    Contains 1 Calx-beta domain.
    Contains 12 CSPG (NG2) repeats.
    功能Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料FREM1 is a 2,179 amino acid protein that contains one C-type lectin domain, one Calx-beta domain and twelve CSPG repeats. Localized to the basement membrane of embryonic epidermal cells and secreted into extracellular space, FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. FREM1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

     

     

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