CD45 Rabbit pAb, FITC conjugated(bs-10599R-FITC)-100ul产品图
文献支持

CD45 Rabbit pAb, FITC conjugat

ed(bs-10599R-FITC)-100ul
收藏
  • ￥2980
  • Bioss已认证
  • bs-10599R-FITC
  • 2025年10月15日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
10 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品

    相关阅读

    细胞污染识别与处理全攻略：5 种常见类型+关键误区Cytoscape 教程来了！快速实现顶刊同款通路网络图五大应用案例：Mustang Q 膜层析应用全解析1 个小工具，一次性搞定流程图、质粒图谱和信号通路图
    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      100ul

    产品编号bs-10599R-FITC
    英文名称CD45 Rabbit pAb, FITC conjugated
    中文名称FITC标记的白细胞共同抗原抗体
    英文别名B220; CD 45; CD-45; CD45; cd45 antigen; ec3.1.3.48; CD45R; GP180; GP180; GP 180; L CA; LCA; L-CA; Leukocyte common antigen; LY5; Ly-5 glycoprotein; Protein tyrosine phosphatase receptor type C; Protein tyrosine phosphatase receptor type c polypeptide; protein tyrosine phosphatase, receptor type, C; Receptor-type tyrosine-protein phosphatase C; PTPRC; PTPRC_HUMAN; SCID due to PTPRC deficiency; T200; T200 glycoprotein; T200 leukocyte common antigen; Human homolog of severe combined immunodeficiency due to PTPRC deficiency.
    产品应用Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CD45
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Angiogenesis > Endothelial Cell Markers

    Immunology > Adaptive Immunity > B Cells > CD

    Immunology > Adaptive Immunity > Regulatory T Cells

    Immunology > Adaptive Immunity > T Cells > CD

    Immunology > Cell Type Markers > CD > Non-lineage

    Neuroscience > Cell Type Marker > Glia marker > Microglia marker

    Signal Transduction > Protein Phosphorylation > Tyrosine Phosphatases

    Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage

    Stem Cells > Hematopoietic Progenitors > Lymphoid > NK Cell Lineage

    Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage

    Stem Cells > Hematopoietic Progenitors > Myeloid > Dendritic Cell Lineage

    Stem Cells > Hematopoietic Progenitors > Myeloid > Mast Cell Lineage

    Stem Cells > Hematopoietic Progenitors > Myeloid > Monocytic Lineage

    Stem Cells > Hematopoietic Progenitors > Myeloid > Neutrophil Lineage

    Stem Cells > Hematopoietic Progenitors > Surface Molecules

    亚基Binds GANAB and PRKCSH. Interacts with SKAP1. Interacts with DPP4; the interaction is enhanced in a interleukin-12-dependent manner in activated lymphocytes. Contains 2 tyrosine-protein phosphatase domains.
    亚细胞定位Membrane; Single-pass type I membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts.
    翻译后修饰Heavily N- and O-glycosylated.
    相似性Belongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 2 tyrosine-protein phosphatase domains.
    功能Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}

     

    产品细节图片1
    Blank control:Mouse thymus.
    Primary Antibody (green line): Rabbit Anti-CD45 antibody (bs-10599R-FITC)
    Dilution: 2μg /10^6 cells;
    Isotype Control Antibody (orange line): Rabbit IgG .
    Protocol
    The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature.Acquisition of 20,000 events was performed.
    产品细节图片2
    Blank control:Mouse spleen.
    Primary Antibody (green line): Rabbit Anti-CD45 antibody (bs-10599R-FITC)
    Dilution: 2μg /10^6 cells;
    Isotype Control Antibody (orange line): Rabbit IgG .
    Protocol
    The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. Acquisition of 20,000 events was performed.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献
    [1]Comparison of the differentiation abilities of bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells toward nucleus pulposus-like cells in three-dimensional culture.
    PMID:34373704Exp Ther Med2021-09
    [2]Cell sheets of co-cultured BMP-2-modified bone marrow stromal cells and endothelial progenitor cells accelerate bone regeneration in vitro.
    PMID:31602206Exp Ther Med2019-11
    相关实验

    • 避坑指南！小鼠组织里精准圈定白细胞完整策略

      免疫细胞与基质细胞。 首先，在FSC-A vs SSC-A图中通过R0圈定计数微球用于定量，并利用R1门排除碎片杂质。 接着进行谱系分离：在R1门内依据CD45、CD326及CD31的表达差异，将细胞精准划分为白细胞（R2）、上皮细胞（R3）和内皮细胞（R4），有效区分了造血细胞与结构细胞。 最后，对各亚群进行死活染料（FVD）分析，剔除死细胞（R5），从而获得存活的白细胞（R6）、上皮细胞（R7）及内皮细胞（R8）。 这套“去碎片-分谱系-除死细胞”的严密流程，为后续肿瘤微环境研究提供了高纯

    • T细胞耗竭与干性调控分子机制及其对肿瘤微环境的影响

      CXCR5和Ly108（SLAMF6），部分还高表达CD62L；过渡性耗竭T细胞（TEX-Trans）为CD101−TIM3+；终末耗竭T细胞（TEX-Term）则表现为CD101+TIM3+CD69+；而效应样耗竭T细胞（eff-like TEX）高表达KLRG1和CX3CR1。相比之下，在急性感染中，效应T细胞（TEFF）为KLRG1hiCD127lo，记忆前体细胞（TMP）为KLRG1loCD127hi。记忆T细胞进一步分为：干细胞样记忆（TSCM，CD62L+CD45RA+CCR7+IL-7R

    • 技术五：MACS(磁珠分选)小鼠细胞分选与分析试剂

      Isolation Kit CD5(Ly-1) MicroBeadsCD8a(Ly-2) MicroBeadsCD8a+ T Cell Isolation Kit CD25 MicroBead KitCD62L(L-selectin) MicroBeadsAnti-MHC class II MicroBeadsCD4-FITC/PE/APCCD8a-FITC/PE/APCCD25-PECD62L-FITC/PE/APCCD90-FITC/PE/APC细胞因子分泌细胞Mouse IFN-r Secretion

    查看更多相关实验 >
    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Rabbit Monoclonal CD45 Antibody (PTPRC/1975R) [FITC]
    ￥500
    北京百奥创新科技有限公司
    2025年07月11日询价
    IL-4R Polyclonal Antibody FITC Conjugated[C91726FITC]
    询价
    南京赛戈巍生物科技有限公司
    2025年09月22日询价
    R107.2 Polyclonal Antibody（多克隆抗体）, FITC conjugated | R107.2 Antibody, FITC conjugated | R107.2抗体, FITC conjugated
    ￥880
    武汉研升生物科技有限公司
    2026年03月28日询价
    FITC Mouse Anti-Rat CD45 Antibody (S-R591)
    ￥200
    杭州斯达特生物科技有限公司
    2026年09月08日询价
    R107.2 Antibody (FITC)/R107.2 Antibody (FITC)/R107.2 Antibody (FITC)
    询价
    艾美捷科技有限公司
    2025年07月10日询价
    文献支持
    CD45 Rabbit pAb, FITC conjugated(bs-10599R-FITC)-100ul
    ￥2980