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- Bioss
- bs-17320P
- 2025年10月16日
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500ug
| 产品编号 | bs-17320P |
| 英文名称 | TEFF1 Antibody Blocking Peptide |
| 中文名称 | TEFF1蛋白封闭多肽 |
| 英文别名 | Tomoregulin-1 precursor; C9orf2; C9orf3 TMEFF1; C9orf30 TMEFF1; C9orf30 TMEFF1 fusion protein; Cancer/testis antigen family 120 member 1; CT120.1; H 7365; H7365; MSANTD3-TMEFF1 readthrough; TEFF 1; TEFF1; TEFF1_HUMAN; TMEFF 1; TMEFF1; Tomoregulin-1; TR 1; TR-1; TR1; Transmembrane protein with EGF like and two follistatin like domains 1; Transmembrane protein with EGF-like and one follistatin-like domain. |
| 纯化方法 | HPLC |
| 亚基 | May interact with ST14. |
| 亚细胞定位 | Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Membrane; Single-pass type I membrane protein. Isoform 3: Secreted. |
| 组织特异性 | Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate. |
| 相似性 | Belongs to the tomoregulin family. Contains 1 EGF-like domain. Contains 2 Kazal-like domains. |
| 功能 | May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Tomoregulin-1 precursor is a single-pass type I membrane protein thought to be a tumor suppressor in brain cancers. Its expression is down-regulated in these tumors as compared to control brain tissues. In addition, it might also inhibit NODAL and BMP signaling during neural patterning. There are 2 isoforms produced by alternative splicing. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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