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- bs-12039P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-12039P |
| 英文名称 | GDE1 Antibody Blocking Peptide |
| 中文名称 | 膜蛋白相互作用蛋白GDE1 (MIR16) 封闭多肽 |
| 英文别名 | GDE1; GDE1_HUMAN; EC 3.1.4.44; Glycerophosphodiester phosphodiesterase 1; Glycerophosphoinositol glycerophosphodiesterase GDE1; Membrane interacting protein of RGS16; Membrane-interacting protein of RGS16; RGS16 interacting membrane protein; RGS16-interacting membrane protein; Lysophospholipase D GDE1. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with RGS16. Interacts with PRAF2. |
| 亚细胞定位 | Cytoplasmic. Membrane; Multi-pass membrane protein. |
| 组织特异性 | Widely expressed. |
| 翻译后修饰 | N-glycosylated |
| 相似性 | Belongs to the glycerophosphoryl diester phosphodiesterase family. Contains 1 GDPD domain._x000D_ |
| 功能 | MIR6 has glycerophosphoinositol phosphodiesterase activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. |
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GDE1 | MIR16 Ab Blocking Peptide(bs-12039P)-500ug
￥880
