- ￥880
- Bioss
- bs-13320P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-13320P |
| 英文名称 | TUBGCP4 Antibody Blocking Peptide |
| 中文名称 | γ-微管蛋白GCP4封闭多肽 |
| 英文别名 | 76P; FLJ14797; Gamma tubulin complex component 4; Gamma tubulin ring complex protein (76p gene); Gamma tubulin ring complex protein; GCP 4; GCP4; h76p; hGCP4; Hgrip76; TUBGCP 4; TUBGCP4; Tubulin gamma complex associated protein 4; GCP4_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microtubules > Tubulin Tags & Cell Markers > Subcellular Markers > Organelles > Centrosome |
| 亚基 | Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6. Interacts with NINL. |
| 亚细胞定位 | Centrosome. |
| 组织特异性 | Ubiquitously expressed. _x000D_ |
| 相似性 | Belongs to the TUBGCP family. _x000D_ |
| 功能 | GCP4 is a component of the gamma-tubulin complex which is necessary for microtubule nucleation at the centrosome. GCP4 shows sequence identity with the C-terminal regions of human centrosomal proteins 103p (TUBGCP2) and 104p (TUBGCP3). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex-associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP4 (gamma-tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the gamma-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation. |
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TUBGCP4 | GCP4 Ab Blocking Peptide(bs-13320P)-500ug
￥880
