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- Bioss
- bs-1726P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-1726P |
| 英文名称 | ERCC1 Antibody Blocking Peptide |
| 中文名称 | DNA切除修复蛋白1封闭多肽 |
| 英文别名 | Excision Repair Cross Complementing 1; DNA excision repair protein ERCC-1; COFS4; UV20; DNA excision repair protein ERCC1; ERCC 1; Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1; Excision repair protein; UV 20; UV20;DNA excision repair protein ERCC-1. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Tumor biomarkers Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > Nucl. Excision Repair |
| 亚基 | Heterodimer composed of ERCC1 and XPF/ERRC4. |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the ERCC1/RAD10/SWI10 family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009] |
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ERCC1 Antibody Blocking Peptide(bs-1726P)-500ug
￥880
