- ￥880
- Bioss
- bs-22564P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-22564P |
| 英文名称 | UBF1 Antibody Blocking Peptide |
| 中文名称 | RNA聚合酶I封闭多肽 |
| 英文别名 | UBF; NOR 90; Nucleolar transcription factor 1; UBF 1; UBF-1; UBF; UBTF; Autoantigen NOR-90; Upstream-binding factor 1; Upstream binding factor 1; upstream binding transcription factor, RNA polymerase I; UBF1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Polymerase associated factors > Pol I Transcription |
| 亚细胞定位 | Nucleus |
| 翻译后修饰 | Phosphorylated and activated by PIK3CA. |
| 相似性 | Contains 6 HMG box DNA-binding domains. |
| 功能 | Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011] |
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UBTF | UBF1 Ab Blocking Peptide(bs-22564P)-500ug
￥880
