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Human MAOA Ready-To-Use IHC Ki

t(IHC0664H)-50T
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  • ¥3200
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  • IHC0664H
  • 2025年10月15日
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      50T

    产品编号 IHC0664H
    英文名称 Human MAOA Ready-To-Use IHC Kit
    中文名称 人单氨氧化酶A即用型免疫组化试剂盒
    英文别名 MAOA; Amine oxidase [flavin containing] A; EC 1.4.3.4; MAO A; MAO-A; Maoa; Monoamine oxidase A; Monoamine oxidase type A; AOFA_HUMAN
    产品应用 IHC-P

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 Human
    亚基 Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer (By similarity).
    亚细胞定位 #Membrane #Mitochondrion #Mitochondrion outer membrane
    相似性 Belongs to the flavin monoamine oxidase family.
    功能 Catalyzes the oxidative deamination of primary and some secondary amines such as neurotransmitters, and exogenous amines including the tertiary amine, neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), with concomitant reduction of oxygen to hydrogen peroxide and participates in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:11049757, PubMed:11134050, PubMed:20493079, PubMed:8316221, PubMed:8665924). Preferentially degrades benzylamine and p‌‌henylethylamine (PubMed:11049757, PubMed:11134050, PubMed:20493079, PubMed:8316221, PubMed:8665924).
    保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
    背景资料 This gene encodes monoamine oxidase A, an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the mitochondrial outer membrane. The gene is adjacent to a related gene on the opposite strand of chromosome X. Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome.

     

    应用 推荐稀释比例

     

    Immunohistochemical analysis of paraffin embedded Human hepatocellular carcinoma tissue slide using IHC0664H (Human MAOA Kit).

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