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Peroxiredoxin-5 Rabbit pAb, AP

conjugated(bs-22754R-AP)-100ul
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  • ¥2980
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  • bs-22754R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-22754R-AP
    英文名称Peroxiredoxin-5 Rabbit pAb, AP conjugated
    中文名称AP标记的过氧化还原酶5抗体
    英文别名Alu corepressor 1; Antioxidant enzyme B166; AOEB166; Liver tissue 2D-page spot 71B; PLP; Peroxiredoxin V; Prx-V; Peroxisomal antioxidant enzyme; TPx type VI; Thioredoxin peroxidase PMP20; PRDX5; PRDX5_HUMAN
    产品应用IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Peroxiredoxin-5
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Apoptosis > Intracellular > Associated Proteins

    Cell Biology > Cell Cycle > Cell differentiation

    亚基Monomer.
    亚细胞定位Isoform Mitochondrial: Mitochondrion._x000D_
    Isoform Cytoplasmic+peroxisomal: Cytoplasm. Peroxisome.
    组织特异性Widely expressed.
    相似性Belongs to the peroxiredoxin 2 family._x000D_
    Contains 1 thioredoxin domain
    功能Reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Involved in intracellular redox signaling.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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    图标文献和实验
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      : https://doi.org/10.1016/j.immuni.2023.02.004 参考文献: 1 Fang, R. et al. Recent advances in the activation and regulation of the cGAS-STING pathway. Advances in Immunology 156, 55-102, doi:10.1016 /bs.ai.2022.09.003 (2022). 2 Posor, Y. et al. 

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