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100ul
| 产品编号 | bs-4198R-Bio |
| 英文名称 | Endothelin B Receptor Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的内皮素B受体抗体 |
| 英文别名 | ABCDS; Ednra; Ednrb; EDNRB_HUMAN; Endothelin B receptor; Endothelin B receptor precursor; Endothelin receptor Non selective type; Endothelin receptor non-selective type; Endothelin receptor type B; ET B; ET-B; ET-BR; ETB; ETRB; Hirschsprung disease 2; HSCR; HSCR2; EDNRB; HSCR; WS4A. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Endothelin B Receptor |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells. |
| 翻译后修饰 | Palmitoylation of Cys-402 was confirmed by the palmitoylation of Cys-402 in a deletion mutant lacking both Cys-403 and Cys-405. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily. |
| 功能 | Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Endothelin receptor type B (ETRB) is a G protein-coupled receptor that activates a phosphatidylinoitol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. A splice variant (SVR), differing in the intracellular C terminal domain, has been described for this receptor. Both WT and the variant bind ET1. However, they exhibit different responses upon binding - suggesting that these two variants are functionally distinct. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验Characterization of Angiotensin II Receptors
., Herblin, W.F., Ardecky, R.J., McCall, D.E., Carini, D.J., Duncia, J.V., Pease, L.J., Wexler, R.R., Wong, P.C., Johnson, A.L., and Timmermans, P.B.M.W.M. 1989a. Identification of angiotensin II receptor subtypes. Biochem. Biophys. Res. Commun. 165:196‐203
缩写 全称 中文 AA autoantibody 自身抗体 AAF aminoacetylfluorescence 氨乙酰基荧光 Ab antibody 抗体 ABC avidin-biotin peroxidase complex 抗生物素(亲合素)-生物素-过氧化物酶复合物 ACh acetycholine 乙酰胆碱 AChR acetycholine receptor 乙酰胆碱受体 AChRAb acetycholine
【申请上传】Current Protocols in Immunology
Immunocompromised Animals Unit 1.3 Handling and Restraint Unit 1.4 Anesthesia Unit 1.5 Animal Identification Section II Use of Mouse, Rat, Hamster, and Rabbit Unit 1.6 Parenteral Injections Unit 1.7 Blood Collection Unit 1.8 Euthanasia Section III Selected
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