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KLF2 Rabbit pAb, Biotin conjug

ated(bs-22855R-Bio)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-22855R-Bio
  • 2025年12月02日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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      100ul

    产品编号bs-22855R-Bio
    英文名称KLF2 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的肺Kruppel样因子抗体
    英文别名Kruppel like factor 2; Kruppel like factor; Kruppel like factor LKLF; Kruppel-like factor 2(lung); Lung krueppel like factor; Lung Kruppel like zinc finger transcription factor; KLF 2; Klf2; KLF2_HUMAN; Krueppel-like factor 2; Lklf; Lung krueppel like factor; Lung krueppel-like factor; Lung Kruppel like zinc finger transcription factor
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human KLF2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic inhibitory factors

    Cardiovascular > Vasculature > Endothelium

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Krueppel like factor

    Epigenetics and Nuclear Signaling > Transcription > Krueppel like factor

    亚基Interacts with WWP1.
    亚细胞定位Nucleus.
    翻译后修饰Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein.
    相似性Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 3 C2H2-type zinc fingers.
    功能Binds to the CACCC box in the beta-globin gene promoter and activates transcription .
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011]

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

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