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KIF18B Rabbit pAb(bs-22415R)-5

0ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-22415R
  • 2025年10月25日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-22415R
    英文名称KIF18B Rabbit pAb
    中文名称驱动蛋白家族成员18B抗体
    英文别名Kinesin family member 18B; KI18B_HUMAN; Kinesin-like protein KIF18B.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse, Dog, Cow, Horse, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human KIF18B
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量94 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Cell Cycle > Cell Division > Other cell division antibodies

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin-like

    亚基Interacts with MAPRE1; this interaction is required for efficient accumulation at microtubule plus ends. Interacts with KIF2C at microtubule tips; this interaction increases the affinity of both partners for microtubule plus ends and is required for robust microtubule depolymerization. KIF2C phosphorylation by AURKA or AURKB strongly reduces KIF18B-binding.
    亚细胞定位Cytoplasmic, Nuclear and Plasma membrane
    组织特异性Shows a prominent expression in the amygdala.
    相似性Belongs to the kinesin-like protein family.
    Contains 1 kinesin-motor domain.
    功能May play an important role in regulating cell division.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The Kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual Kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events, including endocytosis and transcytosis. KIF18B (kinesin family member 18B) is an 864 amino acid nuclear and cytoplasmic protein that belongs to the kinesin-like protein family. Containing one kinesin-motor domain, KIF18B is dominantly expressed in amygdala. During mitosis, KIF18B is suggested to be closely associated with astral microtubules emanating from the spindle pole during prometaphase and metaphase. KIF18B may play an important role in regulating cell division. KIF18B exists as four alternatively spliced isoforms and is encoded by a gene located on human chromosome 17q21.31.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    P‌‌araformaldehyde-fixed, paraffin embedded (rat lymphoid); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KIF18B) Polyclonal Antibody, Unconjugated (bs-22415R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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    KIF18B Rabbit pAb(bs-22415R)-50ul/100ul/200ul
    ¥1180 - 2800